This study evaluated and compared the efficacy of a live (intermediate plus strain) and two killed (produced from intermediate plus and intermediate strains of viruses) infectious bursal disease vaccines in commercial Isa brown cockerel chicks. Two hundred and eighty, one day old chicks were divided into four groups of seventy chicks each. Group 1, 2 and 3 were vaccinated with live vaccine, kil...

In the current study, we investigate changes in CD4+CD25+ cells in chickens during infectious bursal disease virus (IBDV) infection. The percentage of CD4+CD25+ cells in lymph organs, e.g., the thymus, spleen, bursa of Fabricius and peripheral blood, during the first 1-5 days post infection (dpi) was assessed by flow cytometry. The data revealed a remarkable decrease in the percentage of CD4+CD...

Infectious bursal disease (IBD) is an acute, highly contagious viral disease of young chickens. It is most often found in highly concentrated poultry producing areas throughout the world. IBD is caused by a virus that is classified as a member of the genus Avibirnavirus of the family Birnaviridae (Leong et al., 2000), which is characterised by a bisegmented dsRNA genome (Müller et al., 1979, Ki...

Abstract: This study was conducted to characterize infectious bursal disease virus (IBDV) isolates collected from different parts of Iran during 2005-2006. Pooled bursal samples from 49 broiler and layer pullet flocks suspected to IBD infection were collected and processed. A reverse transcriptase-polymerase chain reaction (RT PCR) procedure was used to amplify a VP2 gene fragment (743 bp) from...