Poly(lactide-co-glycolide) (PLGA) is used in many biomedical applications because it is biodegradable, biocompatible, and FDA approved. PLGA can also be processed into porous tissue scaffolds, often through the use of organic solvents. A static light scattering experiment showed that 75/25 PLGA is well solvated in acetone and methylene chloride, but forms aggregates in chloroform. This led to a...

We describe a method for efficiently extracting basic, neutral, and weakly acidic drugs from plasma for toxicological analysis by gas chromatography-mass spectrometry (GC/MS). The 2-mL plasma sample is diluted with an equal volume of saturated NaCl containing triethylamine, 10 mmol/L, and then extracted twice with 4 mL of an equivolume solution of dichloromethane/acetone. The organic (top) phas...

Isolation and enrichment of multiclass pesticides’ residue, namely, fungicides (benalaxyl), herbicides (atrazine), carbamate insecticides (carbofuran), organophosphate (chlorpyrifos), organochlorine (4,4′-DDT), pyrethroid (bifenthrin), were made by combining acetone-based salting-out assisted extraction with the dispersive liquid-liquid microextraction (SADLLME) method, followed high-performanc...

Bacteria have evolved numerous defences against antimicrobial agent and drug resistance in pathogen is on rise. This is due to rapid development of multi-drug resistance, limited anti-bacterial spectrum and adverse effects of available anti-microbial agents. This necessitates the search for new antimicrobials with diverse structures and novel mechanism of action. Flowers are mostly used for orn...

Persimmon byproduct upcycling was performed by solvent-assisted extraction (SAE) to obtain dietary fiber (DF). The effect of SAE on DF modulation studied specific beneficial and pathogenic strains before after the in vitro digestion process. Overall, digested samples extracted using acetone as a solvent (dCET) showed higher ( p < 0.05) prebiotic activity scores (PASs) bacteria such Bifidobacter...

Dispersive liquid-liquid microextraction (DLLME) combined with gas chromatography-mass spectrometry (GC-MS) was used for the extraction and determination of 13 polycyclic aromatic hydrocarbons (PAHs) in mineral water samples. In this procedure, the suitable combination of extraction solvent (500 µL chloroform) and disperser solvent (1000 µL acetone) were quickly injected into the water sample (...

Extracts of Riccinus communis were made in mid-polar solvent acetone and non-polar solvent, petroleum ether by using fresh stem, leaves and tender fruits. Bioassay and Minimum Inhibitory Concentration (MIC) was done against various gram positive and gram negative bacteria by agar cup method. Significant activity was found in all acetone extracts against mainly gram positive bacteria and some gr...