نتایج جستجو برای: vrsa
تعداد نتایج: 217 فیلتر نتایج به سال:
UNLABELLED Methicillin-resistant Staphylococcus aureus (MRSA) strains are leading causes of hospital-acquired infections in the United States, and clonal cluster 5 (CC5) is the predominant lineage responsible for these infections. Since 2002, there have been 12 cases of vancomycin-resistant S. aureus (VRSA) infection in the United States-all CC5 strains. To understand this genetic background an...
Background: Staphylococcus aureus is one of the bacteria under the genus Staphylococcus which is a gram-positive coccus. It is microscopically observed as individual organisms, in pairs and in irregular, grapelike clusters. S. aureus is non-motile and non-spore forming bacteria. It is one of the most common community and nosocomial pathogen. It mainly causes skin and soft tissue infections as i...
A study was conducted to determine plasmid mediated methicillin and vancomycin resistant Staphylococcus aureus along with plasmid profiling and detection of vancomycin resistance genes. This study was carried out in the Department of Microbiology and Fermentation Technology, Sam Higginbottom Institute of Agriculture Technology and Sciences, Allahabad, India. The molecular detection of gene was ...
VanA-type Staphylococcus aureus strain VRSA-7 was partially dependent on glycopeptides for growth. The vanA gene cluster, together with the erm(A) and the ant(9)-Ia resistance genes, was carried by the ca. 35- to 40-kb conjugative plasmid pIP848 present at five copies per cell. The chromosomal ddl gene had a mutation that led to a N308K substitution in the d-Ala:d-Ala ligase that resulted in a ...
OBJECTIVE The objective of the study was to investigate the prevalence of vancomycin-resistant Staphylococcus aureus (VRSA). MATERIALS AND METHODS Three hundred and fifty-six S. aureus isolates from the Imam Khomeini hospital in Tehran, Iran, were evaluated for methicillin and decreased vancomycin susceptibility by the microbroth dilution method. The mecA, vanAand vanB genes were targeted by ...
OBJECTIVES Staphylococcus aureus survives inside eukaryotic cells. Our objective was to assess the activity of NZ2114, a novel peptidic antibiotic, against intracellular S. aureus in comparison with established antistaphylococcal agents acting on the bacterial envelope with a distinct mechanism. METHODS The extracellular (broth) and intracellular (THP-1 monocytes) activities of NZ2114 were co...
Emergence of vancomycin-intermediate Staphylococcus aureus (VISA) and vancomycin-resistant S. aureus (VRSA) strains has led to global concerns about treatments for staphylococcal infections. These strains are currently rare even though there is an upward trend in their reported incidence. Therefore, appropriate screening and epidemiological evaluation of VRSA strains can affect future global he...
Background and objective: The medicinal effects of flavonoids are widely described in the literature; however, their antimicrobial against antibiotic resistant bacteria yet to be highlighted. This study was aimed at investigating growth biofilm inhibitory taxifolin, a flavonoid, vancomycin-resistant Staphylococcus aureus (VRSA). Methods: Seven VRSA isolates were used assess antibiofilm influenc...
We aimed to assess the anti-biofilm activity of vancomycin, maltodextrin, and their combination against vancomycin resistant Staphylococcus aureus (VRSA) and vancomycin-susceptible S. aureus (VSSA) strains based on an in vitro static model. Biofilms of 4 VSSA and 2 VRSA strains were grown in a 96-well static model. Vancomycin 2 mM, maltodextrin 10 mM, and both in combination were tested using t...
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