diabetes mellitus is a metabolic disorder affecting carbohydrate, fat and protein metabolism that affects nearly 10% of the population every year. the treatment of diabetes mellitus has been confined to use of oral hypoglycemic agents and insulin, the former being reported to possess serious side effects. this leads to increasing demand for herbal products with antidiabetic factor with little s...

the aim of the study is to examine in-vitro antioxidant and antimicrobial activity of the acetonic and methanolic extracts of the mushrooms boletus aestivalis, boletus edulis and leccinum carpini. antioxidant activity was evaluated by using free radical scavenging activity and reducing power. in addition, total content of phenol and flavonoid in extracts were determined as pyrocatechol equivale...

nitrite intoxication occurs frequently in ruminants and equines. the most common treatment of this disorder is administration of 1% methylene blue, although the use of some antioxidant agents e.g. vitamins and complementary treatment may also be useful. the aim of this study was to evaluate the in vitro antioxidative effects of some vitamins on methemoglobinemia induced by sodium nitrite. for t...

plants with hypoglycemic properties are important in the treatment of diabetes. one of the mechanisms in reducing blood glucose is preventing the digestive absorption of glucose. the aim of this study was to evaluate the antioxidant properties of some traditional medicinal plants collected from different regions of iran and their effects on glucose diffusion decrease. the amounts of phenolic co...

Lycopene nanoemulsions were prepared to protect the antioxidant activity and improve the bioaccessibility of lycopene-enriched tomato extract (containing 6% of lycopene) by an emulsification-evaporation method. Lycopene nanoemulsions, with droplet sizes between 100 and 200 nm, exhibited higher anti-radical efficiency and antioxidant activity, than did those smaller than 100 nm. Strong protectab...

New 7-thio derivatives of 6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione have been synthesized by the reaction of 3-cyclohexyl-7-thio-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione with alkylhalogenides. The synthesized compounds were tested for antioxidant activity on the model of Fe(2+)-dependent oxidation of adrenaline in vitro. It was found that the antiradical activity of...

The antioxidant activities of the various extracts and fractions from the herbs of Artemisia selegensis Turcz (AST) were investigated by in vitro and in vivo assays. FRAP, DPPH and ABTS assays were used to evaluate the antioxidant activities of the extracts/fractions in vitro. The effect of water extract (WE) in reducing oxidative stress in male mice was evaluated. Phenolic acid compounds contr...

A series of N-substituted-quinolinone-3-aminoamides and their hybrids containing the alpha-lipoic acid functionality were designed and synthesized as potential bifunctional agents combining antioxidant and anti-inflammatory activity. The new compounds were evaluated for their antioxidant activity and for their ability to inhibit in vitro lipoxygenase as well as for their anti-inflammatory activ...

antioxidant activity of peucedanum pastinacifolium boiss. & hausskn aerial part hydroalcoholic extract (hae) and polyphenolic extract (ppe) as well as their total phenolic and flavonoid contents were studied. phenolic and flavonoid contents were respectively estimated as gallic acid and quercetin equivalents. the in vitro antioxidant activity of two extracts of p. pastinacifolium were evaluated...

The in vitro total antioxidant assay, total phenolic content, DPPH assay, FRAP assay of the acetone extracts from four centric diatoms (Chaetoceros simplex, Skeletonema costatum, Odontella mobiliensis, Coscinodiscus centralis) and three pennate diatoms (Nitzschia closterium, Pleurosigma angulatum and Navicula sp.) were performed. The centric diatom, O. mobiliensis was found higher amount of phe...