We have extensively investigated the mechanical properties of passive eye muscles, in vivo, in anesthetized and paralyzed monkeys. The complexity inherent in rheological measurements makes it desirable to present the results in terms of a mathematical model. Because Fung's quasi-linear viscoelastic (QLV) model has been particularly successful in capturing the viscoelastic properties of passive ...

Human and animal models using electromyography (EMG) based methods have hypothesized that viscoelastic tissue properties becomes compromised by prolonged repetitive cyclic trunk flexion-extension which in turn influences muscular activation including the flexion-relaxation phenomenon. Empirical evidence to support this hypothesis, especially the development of viscoelastic tension-relaxation an...

Spherical cellular aggregates are in vitro systems to study the physical and biophysical properties of tissues. We present a novel approach to characterize the mechanical properties of cellular aggregates using a micropipette aspiration technique. We observe an aspiration in two distinct regimes: a fast elastic deformation followed by a viscous flow. We develop a model based on this viscoelasti...

INTRODUCTION Using traditional experimental methodologies [1,2,3], the skin has to be separated from the subcutaneous tissues in order to determine the tissues’ viscoelastic properties. Thus, the complex collagen fiber network in soft tissue could be damaged when the skin is separated from the subcutaneous tissue. Therefore, the viscoelastic properties of the skin and subcutaneous tissues measu...

periodontal ligament is a thin layer of soft tissue that connects root of a tooth to the surrounding alveolar bone. these ligaments play an important role in initiating tooth movement when loads are applied to teeth with orthodontic appliances. the majority of such soft tissues exhibit as viscoelastic bodies or have a time-dependent behavior. due to the viscoelastic behavior of the periodontal ...

It is widely accepted by now that the mechanical characteristics of cells and tissues play an important role in numerous biological processes, such as early morphogenesis [1, 2], signal transduction [3], cell adhesion [4], and even stem cell differentiation [5, 6]. In particular, it was suggested and experimentally demonstrated that a number of phenomena in embryonic tissues can be interpreted ...

From a medical engineering point of view, dynamic properties viscoelastic materials in high strain rate region (> 103 s −1) are considerably important for understanding influences recent minimally invasive surgical techniques with lasers, ultrasounds, and shock waves on biological tissues. In this article, new rheological method via inverse analysis laser-induced inertial micro cavitation pheno...

needle insertion is a minimally invasive technique in diagnosing and treating tumors. however, to perform a surgery accurately, the tissue should have minimum amount of displacement during needle insertion so that it reaches the target tissue. therefore, the tissue membrane has to move less to decrease rupturing under the membrane. in this study, the effect of different design parameters on dis...