The purpose of this study was to evaluate the effects of orthodontic treatment, involving the extraction of four premolars, on vermilion height and lip area. Twenty-eight female patients (mean 21.9 ± 3.1 years) who were diagnosed with bimaxillary protrusion were selected for this study to be treated by extraction of four premolars. The control group consisted of 28 female volunteers (mean 25.0 ...

Plasmoacanthoma and plasma cell cheilitis are rare disorders of obscure etiology characterized by a plasma cell infiltrate. An 80-year-old woman presented with a verrucous, fleshy, skin colored plaque over lips, gingiva, and the palate and painful swallowing for over a period of 6 months. Histopathology of the lesion showed dense infiltrate of plasma cells. The lesions resolved completely after...

Exposure to high sugar diet (HSD) serves as an experimental model of insulin resistance (IR) and type 2 diabetes (T2D) in mammals and insects. Peripheral IR induced by HSD delays emergence of pupae from larvae and decreases body weight of Drosophila imago. Understanding of mechanisms of IR/T2D is essential for refining T2D prevention and treatment strategies. Dysregulation of tryptophan (TRP) -...

3D models of the lips have been developed in the framework of an audiovisual articulatory speech synthetizer. Unlike most of the regions of the human face, the lips are essentially characterized by their border contours. The internal and external contours of the vermilion zone can be fitted by means of algebraic equations. The coefficients of these equations must be controlled so that the lip s...

The Van der Woude syndrome is a rare autosomal dominant developmental malformation usually associated with bilateral lower lip pits. These congenital lip pits appear clinically as a malformation in the vermilion border of the lip, with or without excretion. As a genetic defect has been identified as a microdeletion of chromosome bands 1q32-q41, genetic counselling of patients may be considered....

Spindle cell lipoma (SCL) is a rare distinct variant of lipoma, which presents as a painless, circumscribed, slow-growing, superficial lesion on the lip and can mimic a minor salivary gland tumour. We present a slow growing lower lip lesion and its management. Case Report. A 38-year-old female gave an eight-year history of a slow-growing mass on her lower lip with intermittent change in size. S...

Keratoacanthoma (KA) is a benign epithelial proliferative lesion which frequently occurs on the sun exposed areas of the skin. KA originates within the pilosebaceous apparatus of the skin and may be solitary or multiple. Solitary KA can be difficult to differentiate from squamous cell carcinoma (SCC) both clinically and microscopically. However, the clinical course of the lesion and its ability...

In actinic cheilitis, the current view is that the keratinocytes have undergone transformation forming a field of epithelium with the potential for neoplastic transformation. Clinical features include diffuse and poorly demarcated atrophic, erosive or keratotic plaques that may affect some parts of, or the entire vermilion border. Fair-complexioned people, those with albinism and people with ev...

Squamous cell carcinoma is the most common malignancy of the lower lip. Environmental factors such as ultraviolet light exposure, arsenic and smoking are contributing factors to the increasing incidence. Mohs surgery is the treatment of choice ensuring the lowest recurrence rates. The closure of the surgical defects, however, can be a challenge. Multiple and versatile methods of reconstructing ...

Actinic cheilitis (AC) is a precancerous condition of the lip that primarily affects people with Fitzpatrick skin types I and II as a result of chronic exposure to solar irradiation. Additional factors include poor oral hygiene, chronic lip irritation, and excessive tobacco use. The clinical spectrum of AC is varied and may include erythema, leukoplakia, scaling, atrophy, dryness, fissures, ulc...