Rapid leftward septal motion (RLSM) during early left ventricular (LV) diastole is observed in patients with pulmonary arterial hypertension (PAH). RLSM exacerbates right ventricular (RV) systolic dysfunction and impairs LV filling. Increased RV wall tension caused by increased RV afterload has been suggested to cause interventricular relaxation dyssynchrony and RLSM in PAH. Simulations using t...

The relationship between left ventricular diastolic and systolic dyssynchrony in hypertrophic cardiomyopathy (HCM) was investigated by single-cardiac real-time three-dimensional ultrasonography. A total of 52 patients with HCM were selected in Jining No. 1 People's Hospital from July 2016 to June 2017. Additionally, a total of 52 healthy people were selected to serve as the control group. All p...

Interventricular dyssynchrony evaluated with cardiac magnetic resonance is an independent predictor of systolic dysfunction and left ventricular remodeling while intraventricular dyssynchrony is an independent predictor of LV diastolic dysfunction in patients with isolated LBBB. Comprehensive evaluation of both these parameters of dyssynchrony would be useful in selecting patients for cardiac r...

Cardiac resynchronization therapy (CRT) is an established treatment modality for systolic heart failure. Aimed to produce simultaneous biventricular stimulation and correct the lack of ventricular synchrony in selected patients with congestive heart failure, CRT has shown to improve mortality and reduce hospital admissions when compared to medical treatment. At present, the indication criteria ...

Cardiac resynchronisation therapy (CRT) is a recognised therapy for the management of severe left ventricular dysfunction, advanced congestive cardiac failure (NYHA III or IV), ventricular dyssynchrony (either broad LBBB or mechanical dyssynchrony on echocardiography) and failure of optimal medical therapy to achieve improvement in clinical status. Upgrading right ventricular pacemakers or defi...

BACKGROUND Several echocardiographic dyssynchrony indexes have been proposed to identify responders to cardiac resynchronization therapy using tissue velocity and strain. The present study aimed to compare tissue velocity-derived and strain-derived dyssynchrony indexes in patients with or without systolic dysfunction and left bundle-branch block. METHODS AND RESULTS Tissue Doppler imaging was...

Left ventricular (LV) remodeling is well-known complication after myocardial infarction (MI) and numerous studies have emphasized the clinical importance of ventricular remod-eling. 1-4) In these literatures, progressive LV dilatation and decreased LV ejection fraction were major determinants in future development of heart failure and long term survival. That is why early recognition of patient...

Dobutamine stress echocardiography (DSE) has the potential to stratify patients with low-gradient aortic stenosis (AS) but little is known about ventricular dyssynchrony associated with AS. We report the case of a patient who presented AS associated with left ventricular (LV) dyssynchrony. A DSE was performed, which showed no contractile reserve but an increase in LV dyssynchrony. In this patie...

Background: Left ventricular dyssynchrony plays an important role in predicting response to Cardiac Resynchronization Therapy (CRT). Methods: Thirty patients underwent CRT implantation. Assessment of Left Ventricular (LV) dyssynchrony was done through Gated Spect LV phase analysis. Results: Thirty patients received CRT (mean age 58.7 ±9.0, 24 males). CRT implantation had a favorable prognosis o...

background: several competing geometric and hemodynamic factors are suggested as contributing mechanisms for functional mitral regurgitation (mr) in heart failure patients. we aimed to study the relationships between the severity of mr and the qrs duration and dyssynchrony markers in patients with ischemic or dilated cardiomyopathy. methods: w e prospectively evaluated 251 heart failure patient...