As a result of the availability and clinical efficacy of trastuzumab (Herceptin), clinicians are now faced with a dilemma regarding the accurate identification of patients with HER2 overexpression. In the October 2002 issue of ONCOLOGY, Monica Fornier and colleagues critically reviewed the methodologies currently available for HER2 testing in their article, "HER2 Testing and Correlation With Ef...

The FDA has conditionally approved atezolizumab, the first PD-L1 inhibitor, for metastatic urothelial carcinoma, along with a companion diagnostic, the Ventana PD-L1 (SP142) assay. The agency has also expanded nivolumab's indications to include classical Hodgkin lymphoma, making this PD-1 inhibitor the first to be approved for a hematologic malignancy.

A partir de 2022 en nuestro país, se retorna a la normalidad, pero ésta no es exactamente igual pre pandemia, estableciéndose “una nueva normalidad”. La educación debe adecuarse las nuevas circunstancias y el rol del docente acompaña estos cambios, convirtiéndose mediador, favoreciendo procesos formación autogestionados. Es importante que oferta pedagógica sea acorde necesidades, por ello, fina...

AIMS Assessment of hormone receptor expression is part of routine examination of every breast cancer. In this study, we report the characterisation of a novel rabbit monoclonal antibody, clone EP1, directed against oestrogen receptor (ER) α. Additionally, its immunohistochemical performance characteristics in archival tissues are evaluated in normal tissues and two distinct cohorts of breast ca...

This year, Toward a Science of Consciousness will be held at the luxurious, eco friendly Loews Ventana Canyon Resort Hotel. An estimated 600 participants from around the world are expected for the program which will include Plenary and Keynote Talks, Concurrent Talks, Posters, Art Tech Health Demos, Exhibits, Social Events, Side Trips and Pre Conference Activities. The program is below; For fur...

Purpose/Aim of the study: BRAFV600E is an oncogenic point mutation in the MAPK/ERK signaling pathway, which is important for cell proliferation and migration. It has been found to be associated with several malignancies and has also been found in significant proportions of patients with Langerhans cell histiocytosis. A recent mouse model which introduces the BRAFV600E mutations only into dendri...