OBJECTIVE Matrix metalloproteinase (MMP) activity has been linked to abdominal aortic aneurysm (AAA) rupture. Medial neovascularization (MNV), a histopathologic characteristic of AAAs, involves proteolytic degradation of extracellular matrix by MMPs to facilitate endothelial cell migration. The role of MNV in aneurysm rupture is unknown. This study investigated whether MNV is increased in aneur...

Objective Magnesium has been implicated in regulating blood pressure and vascular endothelial cell function, but its role the pathophysiology of intracranial aneurysm is not known. Here we performed a Mendelian randomization analysis to investigate association between serum magnesium concentration risk aneurysm. Methods Five single-nucleotide polymorphisms strongly associated with concentration...

A 55-year-old man with a palpable pulsatile mass and pain in his left thigh was presented to us. He had no history of trauma in his left leg, interventions, operation, or medical diseases, including cardiac valve disease, endocarditis, and systemic infection. The size of the aneurysm was 10 cm×7 cm with a mural thrombus in ultrasonography and multidetector computer tomography. There was no evid...

Transapical aortic valve replacement through an apical aneurysm is traditionally contraindicated because of the risk of severe systemic embolization when thrombi are present. However, a chronic fibrotic aneurysm without apical thrombi carries a low risk of distal embolization and can be safely employed for a transapical transcatheter aortic valve replacement in case of absence of an alternative...

A replica of a lethal wide-necked basilar artery aneurysm was created by casting a deceased patient’s brain vessels and then placing the replica in a circuit of pulsating optically clear non-Newtonian fluid. Individual fluid slipstreams were opacified with isobaric dyes, and images were recorded on film. Studies were completed on the vascular replica, then were repeated, first after placement o...

We describe a case involving a ruptured intradural aneurysm of the meningeal branch of the occipital artery arising from the external carotid artery and connecting with the caudal loop of the posteroinferior cerebellar artery (PICA) by the dural fistula. Angiography of the left external carotid artery showed a saccular aneurysm of the occipital artery, but the picture of the left vertebral arte...

Rupture of an intracranial aneurysm is a serious neuro-vascular event requiring immediate management to avoid devastating neurological sequelae. Despite the rapid evolution of endovascular techniques, clipping is still a necessary tool in aneurysms with non-optimal dometo-neck ratio and in younger patients. Occasionally, optimal positioning of an aneurysm clip with optimal obliteration of the a...

Aneurysm of a pulmonary vein is a rare vascular anomaly that is usually discovered incidentally as a pulmonary nodule or mediastinal mass. Most patients do not have any symptoms but some patients can present with dyspnea, hemoptysis, or cerebral thromboembolism. Proper diagnosis is crucial as to avoid unnecessary testing or surgical procedures. We highlight a case of an asymptomatic 59-year-old...

Giant saccular middle cerebral artery aneurysm is rare vascular lesion and few cases have been reported in the literature. Microsurgical clipping applied to treat a giant .A 26 year-male presented with complain severe headache, multiple episodes of vomiting one episode sudden loss conscious since hours prior admission at emergency department. Cerebral Angiography showed (MCA) aneurysm. A standa...

INTRODUCTION Ruptured common iliac aneurysms present with diagnostic and therapeutic challenges. This case describes the successful outcome in a patient with complex vascular surgical history. CASE PRESENTATION An elderly patient presented with abdominal pain confirmed by CT as leaking iliac aneurysm. He had previously undergone an aorto-bifemoral bypass graft for ruptured abdominal aortic an...