Objective (s): Scar formation in injured peripheral nerve bed causes several consequences which impede the process of nerve regeneration. Several animal models are used for scar induction in preclinical studies which target prevention and/or suppression of perineural scar. This study evaluates the translational capacity of four of physical injury models to induce scar formation aro...

Analysis of scars in various conditions is essential, but no consensus had been reached on the scar assessment scale to select for a given condition. We reviewed papers to determine the scar assessment scale selected depending on the scar condition and treatment method. We searched PubMed for articles published since 2000 with the contents of the scar evaluation using a scar assessment scale wi...

BACKGROUND SCAR/WAVE is a principal regulator of pseudopod growth in crawling cells. It exists in a stable pentameric complex, which is regulated at multiple levels that are only beginning to be understood. SCAR/WAVE is phosphorylated at multiple sites, but how this affects its biological activity is unclear. Here we show that dephosphorylation of Dictyostelium SCAR controls normal pseudopod dy...

Background: Urinary tract infection in children may cause renal scar formation, which can be prevented by early and appropriate treatment. Recent studies showed that single daily injection of gentamycin can produce best effect without increasing the side effects. The aim of this study was to evaluate the rate of renal scar formation when new regime (every other day gentamicin injection) used fo...

background neck reconstruction is considered as one of the most important surgeries in cosmetic and reconstructive surgery. the present study aimed to assess the results of reconstructive surgery of extensive face and neck burning scars using tissue expanders. methods this descriptive prospective study was conducted on 36 patients with extensive burning scars on the neck and face. operation for...

We describe a scar-related reentrant ventricular tachycardia circuit with a proximal segment in an endocardial basal septal scar and an exit in a region of slow conduction in a non-overlapping region of epicardial basal lateral scar. The 12-lead EKG demonstrates criteria for a basal lateral epicardial VT, however the same morphology could be produced with a longer stim-latency with pace mapping...

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purpose: to investigate demographic, clinical and histopathologic features of consecutive exotropia. methods: patients with consecutive exotropia who underwent surgery in farabi hospital between september 2014 and april 2015 were enrolled in this study. after complete ophthalmologic examination and far and near deviation measurement, all patients with negative forced duction test underwent 4-mm...

endometriosis is described as the presence of functioning endometrial tissue (glands and stroma) outside the uterine cavity. the most common location is within the pelvis. however, extra pelvic endometriosis is a fairly uncommon disorder and difficult to diagnose. it can sometimes occur in a surgical scar. scar endometriosis is a rare condition and difficult to diagnose. it mostly follows obste...

Background: Pyelonephritis can lead to renal scar. Objective: To evaluate the effects of betamethasone in preventing renal scarring in rat model of pyelonephritis. Methods: Sixty three female Sprague-Dawley rats were divided into seven groups. Group A was the control. Mannose-sensitive E coli was directly inoculated into the left kidney exposed under general anesthesia in groups C–G. Group B re...