Technology Acceptance Model (TAM) is capable of explaining user behavior across a broad range of end-user computing technologies and user populations. In its original form TAM has been extensively incorporated as a methodology to measure attitude towards technology adoption from users in multiple domains, as well as within financial domain. TAM variations have also been proposed and applied for...

Many organisations today are trying to increase the number of visits to their website, as well as the frequency and duration of their visits once they get there. In this paper, we empirically investigate an extension of the Technology Acceptance Model (TAM, originally developed by Davis, 1989) to explain the individual acceptance and usage of a website. The project extends TAM with two “website...

We recently demonstrated that endoxifen (4-hydroxy-N-desmethyl-tamoxifen), a pharmacogenetically regulated metabolite of tamoxifen, is equipotent to 4-hydroxy-tamoxifen (4-OH-Tam) with respect to estrogen receptor binding and inhibition of 17beta-estradiol (E2)-induced cell proliferation. Endoxifen was also found to be more abundant in human plasma than 4-OH-Tam, and its formation has been show...

Mobile telecommunication operators are under great pressure to launch new profitable data services. However, most of the mobile data services have fallen short of the expectation and have failed on the market. One important reason for the failure of mobile data services is the difficulty to assess user needs and requirements in advance. This paper suggests to use the Technology Acceptance Model...

Tumor-associated macrophages (TAM) form a major component of the tumor stroma. However, important concepts such as TAM heterogeneity and the nature of the monocytic TAM precursors remain speculative. Here, we show for the first time that mouse mammary tumors contained functionally distinct subsets of TAMs and provide markers for their identification. Furthermore, in search of the TAM progenitor...

Three-axis-magnetometers (TAMs) are widely utilized as a key component of attitude determination subsystems and as such are considered the corner stone of navigation for low Earth orbiting (LEO) space systems. Precise geomagnetic-based navigation demands accurate calibration of the magnetometers. In this regard, a complete online calibration process of TAM is developed in the current research t...

The effect of tamoxifen (TAM) on human endometrial carcinoma was investigated in nude mice bearing an estrogen receptor-positive or estrogen receptor-negative tumor. The receptor-negative tumor grew rapidly, and the rates of tumor growth of 17 beta-estradiol or TAM-treated animals were identical to the rate of controls. The estradiol receptor and progesterone receptor (PR) concentrations in the...

Protein S (ProS) and growth arrest-specific 6 (Gas6) bind to phosphatidylserine (PtdSer) and induce efferocytosis upon binding TAM-family receptors (Tyro3, Axl, and Mer). Here, we produced mouse ProS, Gas6, and TAM-receptor extracellular region fused to IgG fragment crystallizable region in HEK293T cells. ProS and Gas6 bound Ca2+ dependently to PtdSer (Kd 20-40 nM), Mer, and Tyro3 (Kd 15-50 nM)...

In this paper, a new method is presented for TAM/wrapper co-optimization based on hybrid genetic algorithm and twodimensional packing problem. In this method, core test is represented by rectangles, and a hybrid genetic algorithm that provides highly optimal solution for two-dimensional packing problem is introduced for TAM allocation and test scheduling. During the scheduling, the TAM width as...

Successful implementation of Information Technology can be judged or predicted from the user acceptance. Technology acceptance model (TAM) is a model that is built to analyze and understand the factors that influence the acceptance of the use of technologies based on the user's perspective. In other words, TAM offers a powerful explanation related to acceptance of the technology and its behavio...