نتایج جستجو برای: vacuolating cytotoxin a vacagenotypes

تعداد نتایج: 13432362  

Journal: :The Journal of infectious diseases 1996
J F Weel R W van der Hulst Y Gerrits P Roorda M Feller J Dankert G N Tytgat A van der Ende

The interrelationship between cytotoxin-associated gene A (CagA), vacuolating cytotoxin (VacA), and Helicobacter pylori-related diseases was investigated in 155 H. pylori-infected patients. Four (7%) of 60 subjects had mixed cagA+ and cagA- H. pylori infections. The H. pylori isolates from 98.3% of 121 patients with anti-CagA antibodies were cagA+. The occurrence of cagA+ H. pylori among 76 pat...

Journal: :The Kobe journal of medical sciences 2017
Tomoko Inagaki Shin Nishiumi Yoshiyuki Ito Akiyo Yamakawa Yukinao Yamazaki Masaru Yoshida Takeshi Azuma

Helicobacter pylori, which is involved in the pathogenesis of gastroduodenal disease, produces CagA and VacA as major virulence factors. CagA is classified into East Asian and Western types based on the number and sequences of its Glu-Pro-Ile-Tyr-Ala motifs. The vacA gene has three polymorphic regions: the signal (s), intermediate (i), and middle (m) regions. The lowest gastric cancer mortality...

Journal: :Journal of clinical microbiology 2001
K A Ryan L J van Doorn A P Moran M Glennon T Smith M Maher

The prevalence of clarithromycin resistance-associated mutations, the cytotoxin-associated gene (cagA), and the various vacuolating cytotoxin (vacA) genotypes was determined in 50 gastric biopsy specimens from Helicobacter pylori-infected patients, using line probe assays. The clarithromycin resistance-associated mutation A2143G was detected in H. pylori strains from 26% of the specimens, which...

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