A fast and sensitive ultra-high performance liquid chromatography-photodiode array (UHPLC-PDA) method for simultaneous quantification of oleanolic acid (OA) and ursolic acid (UA) in plant materials was developed. A central composite design combined with a response surface methodology was utilized to establish optimal separation conditions. The final separation was accomplished on a Zorbax Eclip...

Background: Vaccinium arctostaphylos L. (Caucasian whortleberry) fruit is used as an anti-hyperglycemic agent for treatment of diabetes mellitus. Objective: The effects of whortleberry fruit and leaf extracts on the blood levels of fasting glucose, HbA1c (glycosylated hemoglobin), insulin, creatinine and liver enzymes SGOT and SGPT in alloxan-diabetic rats as well as LD50s of the extracts in ...

Turkey is one of the most significant countries in the world from the point of view of both fruit genetic resources and amount of fruit production. Around 100 fruit species, including almost all the deciduous fruit species, most of the subtropical and some tropical fruit are grown in Turkey. Among fruits, berry fruits including grapes share 25% of total fruit production of the country. The most...

The Vaccinium genus contains several valuable fruit and ornamental species, among others: highbush blueberry (Vaccinium × corymbosum L.), cranberry (Vaccinium macrocarpon Ait.), and lingonberry (Vaccinium vitis-idaea L.). In some most popular and valuable cultivars, the conventional propagation methods, exploiting hard or soft wood cuttings, are inefficient. The demand for nursery plants could ...

The need to improve pharmacopoeial approaches the standardization of medicinal plant raw materials (MPRMs) and herbal products (HMPs), ensure implementation principle «cross-cutting» in series «medicinal material – phyto-substance product» determine relevance developing new, more rational analysis objects origin. purpose research was theoretical experimental substantiation use reference develop...