Background: Methotrexate (MTX) is used as an antineoplastic drug in the treatment of various cancers and non -cancerous diseases. Ovarian ablation is considered to be effective in delaying recurrence of cancer and increasing survival in young women. When added to chemotherapy, it is less clear that this technique is effective. Uniqueness of the present study is that we used ovariectomized (OVX)...

A 48-year-old woman presented with abdominal fullness and a palpable "mass" in the left lower quadrant. Ultrasonography showed a large, rounded, hypoechoic mass. Contrast-enhanced helical CT of the abdomen demonstrated a well-circumscribed, heterogeneously but vividly enhancing mass. The uterus had a leiomyomatous configuration on CT. Uterus and mass revealed the same enhancing pattern. Thin se...

Although asymptomatic cases naturally occur, congenital mullerian abnormalities can present with infertility, menstrual irregularity and recurrent pregnancy loss. Women with normal reproductive outcomes and recurrent pregnancy loss exhibit approximately 2-4% and 5-10% incidence of various congenital mullerian abnormalities. Following septate uterus, bicornuate uterus and arcuate uterus, unicorn...

prevalence of abortion is higher in women with autoimmune thyroid disease. in the majority of cases, however, no abnormality of thyroid function is detected despite the high levels of antithyroid antibodies. the direct influence of such harmful autoantibodies in female reproductive organs may serve a role in pregnancy loss. in this study, expression of thyroglobulin in the reproductive tissues ...

abstract a32 year-old multigravid patient with 10 weeks of pregnancy was referred to the emergency ward with massive vaginal bleeding and preshock state. suction curettage, laparotomy, uterine artery ligation, macdonald cerclage, and hysterectomy was done, in that order. after hysterectomy and massive transfusion she recovered. when a diagnosis of cesarean scar pregnancy is made in the emergenc...

uterine lymphoma is a rare disease therefore, information regarding histologic type, immunophenotype of tumor cells and etiologic factors are limited. although secondary involvement of the genital tract occurs in up to 40% of cases• of disseminated lymphoma, lymphoma presenting with primary female genital tract . symptomatology is very unusual. we report a case of b-cell lymphoma in the uterine...

Glucose-6-phosphatase-β (G6Pase-β or G6PC3) deficiency, also known as severe congenital neutropenia syndrome 4, is characterized not only by neutropenia but also by impaired neutrophil energy homeostasis and functionality. We now show the syndrome is also associated with macrophage dysfunction, with murine G6pc3(-/-) macrophages having impairments in their respiratory burst, chemotaxis, calcium...

This study was carried out to compare the histomorphological structures of oviductal regions of the apparently healthy adult laying hens (Gallus gallus dometicus) and ducks (Ansa ansa domesticus). For this purpose, 20 hens and 20 female ducks aged between 1–1.5 years were used. After euthanasia, the oviducts were dissected out and all of the gross morphometrical parameters including length, wid...

Zataria multiflora Boiss. is used in Iranian traditional medicine to treat gastrointestinal disorders and menrrhalgia. The inhibitory effect of this herb on rat ileum contractions is also reported. The aim of this study was to investigate the effect of Zataria multiflora Boiss. hydroalcoholic leaf extract (ZHLE) on isolated rat uterus in presence of some known uterus stimulants. Pieces of virgi...