T he field of neurotrophin biology has made great advances in recent years to include a greater understanding of signaling pathways and broader understanding of the diverse biological roles of these molecules. This review will focus primarily on the nerve growth factor family of neurotrophins and how recent descriptions of the molecular function of both the ligands and the receptors have helped...

number of new drugs which have appeared during the last three years have been included and the author has been very wise in exercising a judicious caution in their selection. The sulphanilamide group of drugs which, is still in an experimental stage has received adequate attention. The book has been well written and brings out with great clarity the really important actions and therapeutic uses...

Animal venoms have been used for therapeutic purposes since the dawn of recorded history. Only a small fraction, however, have been tested for pharmaceutical utility. Modern computational methods enable the systematic exploration of novel therapeutic uses for venom compounds. Unfortunately, there is currently no comprehensive resource describing the clinical effects of venoms to support this co...

The kind of land use and intensity of its change is considered as important desertification indices in different models. Land use change is one of the main anthropogenic factors in the desertification. The current research was carried out around Imam Khomeini airport, with an area of 32000 km2, in order to evaluate mentioned area's land use changes effects during 1955-2003 on desertification. T...

Due to the increase of changes in the land uses mainly resulting from humaninterferences, monitoring the changes and evaluating their trend and environmental effectsfor future planning and management are essential. In the present study, an attempt is madeto observe the changes which had occurred in Ardestan area during a period of 30 yearsusing some satellite images. Different kinds of data for...

Adjuvant high dose IVIgs are being used increasingly in a range of immune-mediated and auto-immune diseases. Although numerous immunomodulatory mechanisms have been suggested, the exact mechanisms of action are poorly understood. The efficacy of IVIg in certain diseases has been proven in clinical trials, in so far as IVIg is approved as the therapy of choice for Kawasaki syndrome and idiopathi...

A meta-analysis was performed in an attempt to clarify the proposed relationship between religiosity and psychological adjustment. Specific focus was given to the issue of definition, namely, whether differences in researchers’ conceptualizations of religiosity and mental health could account for the various contradictory findings by psychologists of religion. Analysis of 34 studies conducted d...

Less than a decade after the founding of the American Pharmaceutical Association, the noted American physician Oliver Wendell Holmes, addressing the Massachusetts Medical Society in 1860, made his oft-quoted statement that " ...if the whole materia medica, as now used, could be sunk to the bottom of the sea, it would be all the better for mankind-and all the worse for the fishes. " 1 The pharma...