BACKGROUND Examination of urine for decoy cells (DCs) is a useful screening test for polyomavirus (PV) activation. We explored the significance of the amount of DCs in persistent shedding, PV nephropathy and acute rejection. METHODS A case-controlled study was performed in 88 renal allograft patients who had DCs detected at least once in four or more urine samples. RESULTS Fifty one patient...

Haematophagous insects incorporate a large amount of blood with each meal, producing a big quantity of urine in a few hours to eliminate the excess water and Na(+). Malpighian tubules (MTs) have traditionally been seen as a system that responds to neuroendocrine stimulus. In a related paper, we demonstrated that MTs of Triatoma infestans produce an autonomous endocrine secretion of an allatotro...

Sodium 2,3-dimercapto-1-propane sulfonate (DMPS, Dimaval) is a water-soluble chelating agent that can be given by mouth or systemically and has been used to treat metal intoxication since the 1960s in the former Soviet Union and since 1978 in Germany. To better approximate the body burdens of Hg and As in humans, DMPS-Hg andDMPS-As challenge tests have been developed. The tests involve collecti...

background because of difficulty in obtaining a 24-hour urine collection in children, a random sample of urine is often used to calculate the urinary calcium to creatinine ratio. urinary calcium excretion might be influenced by genetic, geographic area, etc. in this study, the value of urinary calcium, creatinine, sodium and potassium excretion and age–related reference values for urine calcium...

CMAJ • NOVEMBER 10, 2009 • 181(10) © 2009 Canadian Medical Association or its licensors 714 A54-year-old man presented with an 8-week history of episodic palpitations accompanied by chest pain and headache. He had no sweating with the episodes. Investigations included 24-hour urine collection for the presence of metanephrines. One month later, while awaiting the results of the investigations, t...

The region of Diwalwal, dominated by Mt. Diwata, is a gold rush area on Mindanao (Philippines) where approximately 15000 people live. The fertile plain of Monkayo is situated downstream, where people grow crops such as rice and bananas; locally caught fish is eaten frequently. The ore is dug in small-scale mines and ground to a powder by ball-mills while still in Diwalwal. The gold is then extr...

patients and methods this cross-sectional study included a total of 120 adult predialysis ckd patients. forty patients were allocated in each predialysis ckd group of stages 3, 4, and 5. serum ctnt and hs-crp, plasma nt-probnp, and single spot urine albumin creatinine ratio (acr) were measured. ultrasonographic examination of carotid artery was done with 7.5 mhz linear probe in b mode ultrasono...

BACKGROUND We tested minocycline as an anti-proteinuric adjunct to renin-angiotensin-aldosterone system inhibitors (RAASi) in diabetic nephropathy (DN) and measured urinary biomarkers to evaluate minocycline's biological effects. METHODS DESIGN Prospective, single center, randomized, placebo-controlled, intention-to-treat pilot trial. Inclusion. Type 2 diabetes/DN; Baseline creatinine clea...