to evaluate the value of random urinary protein creatinine ratio in prediction of 24h proteinuria in hypertensive pregnancies. method: random urine samples and routine 24h urine collections were collected from hypertensive pregnant women (n=100). reliability of random urinary protein-creatinine ratio was assessed by receiver operator characteristic (roc) curve to detect significant proteinuria ...

The miRNAs in urinary sediment are easy to obtain, which provides a new approach to searching for non-invasive biomarkers of IgA nephropathy (IgAN). Compared with normal controls (n = 3), 214 different miRNAs in the urinary sediment of IgAN (n = 9) were found by miRNA chip assay. By quantitative PCR analysis, miR-25-3p, miR-144-3p and miR-486-5p were confirmed to be significantly higher in IgAN...

objective: present study aimed to evaluate the effects of stress, urge and mixed urinary incontinence on the quality of life and mental health of iranian women with urinary incontinence (ui). materials and methods: this was a cross sectional study of quality of life and mental health among women without and with different types of urinary incontinence (n = 140). quality of life (qol) and mental...

We investigated the polymorphic enzymes cytochrome P450 1A2 (CYP1A2), N-acetyltransferase (NAT2), glutathione S-transferase (GST) M1 (GSTM1), and T1 (GSTT1) in relation to cigarette smoking-associated urinary mutagenicity detected on YG1024 Salmonella typhimurium strain with S9 mix in 97 smokers. In each subject, cigarette smoke intake was checked by analysis of urinary nicotine plus its metabo...

objective(s): in recent years, there has been an increasing amount of study on early diagnosis of kidney injury through sensitive and specific biomarkers. we examined the practical applicability of the urinary levels of nag (n-acetyl-β-d-glucosaminidase), ap (alkaline phosphatase), and ldh (lactate dehydrogenase) as renal dysfunction screening biomarkers in full and pre-term newborns treated wi...

OBJECTIVE The present study was carried out to determine the effect of cadmium exposure on Urinary N-acetyl-beta -D-glucosaminidase and its isoenzymes A and B in workers exposed at cadmium plating. METHODS 50 subjects using cadmium during cadmium plating formed the study group. An equal number of age-sex matched subjects working in administrative section formed the control group. Urinary cadm...

PURPOSE Urinary angiotensinogen has been reported as a marker for the activation of intrarenal renin-angiotensin system (RAS) in various kidney diseases. To investigate the importance of urinary angiotensinogen in diabetic nephropathy, we compared the urinary levels of angiotensinogen, albumin, and α1-microglobulin. MATERIALS AND METHODS Japanese patients with type 2 diabetes at various stage...

objective(s) staphylococcus aureus is both a successful human commensal and a major pathogen. in this study we investigated the genetic diversity of 26 s. aureus isolates recovered from human skin and urinary tract infections. materials and methods typing procedure for the studied s. aureus isolates was performed based on pcr amplification of the aroa gene, which encodes the enzyme 5-enolpyruvy...

Background. Despite enzyme replacement therapy, Fabry nephropathy still progresses. Podocyturia is an irreversible event that antedates proteinuria and leads to chronic renal failure. We evaluated a potential mechanism of podocyte detachment via the expression of the urokinase-type Plasminogen Activator Receptor (uPAR) in urinary podocytes of Fabry patients. Methods. This is a cross-sectional s...

BACKGROUND A number of factors, including gender, age, smoking habits, and occupational exposure, affect the levels of urinary cadmium. Few studies have considered these influences when calculating the benchmark dose (BMD) of cadmium. In the present study, we aimed to calculate BMDs and their 95% lower confidence bounds (BMDLs) for cadmium-induced renal tubular effects in an age-specific popula...