background: common carotid intima-media thickness (cc-imt) measured by ultrasonography as a non-invasive method is nowadays known as a marker for early atherosclerosis. objectives: survey the relationship between serum uric acid and carotid intima-media thickness considering hypertension. materials and methods: this study was designed as a comparative cross-sectional study in northern iran in 2...

?18 Composition, &c. Oxalate of lime nucleus, with uric acid and oxalate of lime alternating. Colour, brown and fawn. Structure, laminated. Uric acid nucleus, with uric acid and a little urate of ammonia. Colour, light fawn, Structure, non-laminated, soft. Uric acid throughout. Colour, fawn. Structure, indistinctly laminated. Urate of lime throughout. Colour, grey. Structure, compact, non-lamin...

The physiological function of organic anion transporter OAT2 (SLC22A7) remains unclear, but since OAT2 transports purine derivatives, it may be involved in renal handling of uric acid, the final metabolite of purine derivatives. In the present study, we studied uric acid transport in stably OAT2-expressing HEK293 cells (HEK293/OAT2). OAT2 mediated uptake, but not efflux, of [(14)C]uric acid. Ur...

Background: Previous studies show that serum level of uric acid is significantly correlated with mortality and functional outcome in patients with ischemic stroke and according to some other studies, ischemic stroke is associated with stenosis of some stenoisis of somespecific brain vessels. The aim of this study was to investigate the frequency of hyperuricemia and its associa...

Uric acid is associated with hypertension and increased renin-angiotensin system activity, although this relationship diminishes after chronic exposure to high levels. Uric acid is more strongly associated with poor outcomes in women compared to men, although whether this is due to a sex-specific uric acid-mediated pathophysiology or reflects sex differences in baseline uric acid levels remains...

in this study, incorporation of iron ion-doped natrolite nanozeolite, multi-wall carbon nanotubes into chitosan-coated glassy carbon electrode for the simultaneous determination of ascorbic acid, epinephrine, uric acid and tyrosine is studied. the results show that the combination of multi-wall carbon nanotubes and iron ion-doped natrolite zeolite causes a dramatic enhancement in the sensitivit...

One proposed mechanism by which alum enhances an immune response is by its ability to induce an inflammatory response that results in the release of uric acid from necrotic cells. Uric acid is thought to be a mediator in enhancing the immune response. The aim of this study was to investigate the immunopotentiating effect of uric acid. Groups of BALB/c mice were injected intraperitoneally with o...

After uric acid was recognized as the causative factor in gout, increased prevalence of renal disease and hypertension in this patient population caught the attention of the medical community. Thus, it has been proposed that uric acid might have caused these disorders. However, uric acid suffered a long period of ignorance in which it was considered a metabolically inert substance. However, rec...

VARIETY of methods is available for tue colorimetric determination of uric acid. In general, these are based on precipitation of proteins, followed by the reduction in an alkaline medium of phosphotungstate by the uric acid ill the protein-free filtrate. Results of colorimetric determinations may at times vary from “true” uric acid values as determined by unease methods. This is because the col...

With considering serum concentration of the uric acid in humans we are observing hyperuricemia and possible gout development. Many epidemiological studies have shown the relationship between the uric acid and different disorders such are obesity, metabolic syndrome, hypertension and coronary artery disease. Clinicians and investigators recognized serum uric acid concentration as very important ...