Objective: Alcea genus belongs to Malvaceae family and this is represented by 85 taxa in the world 21 Flora of Turkey.The flowers contain plenty mucilage are used for treatment respiratory diseases such as asthma cough.Alcea dissecta known ‘Govik, Hiro, Hero’ Turkey, leaves species have been asthma,injury, colds, gastrointestinal Turkey. To best our knowledge, there no report on effect extracti...

Presence of heavy metals (HM) in agricultural soil is a major hazard to the soil-plant system. In the present study, soil samples (0-5 cm depth) were taken in order to determine the effects of heavy metal pollution on soil enzymes like dehydrogenase, alkaline phosphatase (APA), urease (UA) protease, cellulose, invertase, beta glucosidase and amylase. Results showed that Cadmium (Cd) significant...

The antimicrobial effect of a novel flavonoid (7-O-butylnaringenin) on Helicobacter pylori 26695, 51, and SS1 strains and its inhibitory effect on the urease activity of the strains were evaluated and compared with those of several natural flavonoids. First, various flavonoids were screened for antimicrobial activities using the paper disc diffusion method. Hesperetin and naringenin showed the ...

The inhibition of urease from Sporosarcina pasteurii (SPU) and Canavalia ensiformis (jack bean, JBU) by a class six aromatic poly-hydroxylated molecules, namely mono- dimethyl-substituted catechols, was investigated on the basis inhibitory efficiency catechol scaffold. aim to probe key step mechanism proposed for SPU catechol, sulfanyl radical attack ring, as well obtain critical information ef...

A series of eighteen 1,3,4-oxadiazole derivatives have been synthesized by treating aromatic acid hydrazides with carbon disulfide in ethanolic potassium hydroxide yielding potassium salts of 1,3,4-oxadiazoles. Upon neutralization with 1 N hydrochloric acid yielded crude crystals of 1,3,4-oxadiazoles, which were purified by recrystallization in boiling methanol. The synthesized 1,3,4-oxadiazole...

Meralluride, mercaptomerin, ethacrynic acid, and penicillamine inhibited urease activity of Proteus mirabilis. The activity of the organic mercurials and ethacrynic acid was markedly inhibited by human and dog urine. Antiurease activity could not be detected in the urine of a human and a dog given meralluride by injection. Urine from patients receiving penicillamine also failed to inhibit ureas...

New series of spiro indeno[1,2-b]pyrido[2,3-d]pyrimidine-5,3'-indolines as new urease inhibitors were synthesized by the catalytic procedure in high yield and short reaction time. In this method, biacidic carbon was prepared as a novel heterogeneous acid and was subsequently used as an efficient catalyst. The inhibitory activities of synthesized compounds were tested against Jack bean urease us...

Amaç: Bu araştırmada Malva neglecta Wallr.’nın kimotripsin ve üreaz enzimlerini inhibe edici aktivitesinin tespiti ayrıca antioksidan aktivitesi, toplam fenol flavonoit içeriğinin belirlenmesi amaçlanmıştır. Yöntem: 2021 yılı Nisan-Haziran ayları arasında bitkinin çiçekli meyveli toprak üstü kısımlarından metanol su ekstresi hazırlanmış bu ekstrelerin in vitro inhibitör aktivitesi belirlenmişti...

In order to evaluate the influence of substitution on biological properties of Schiff bases and their metal complexes, a series of differently substituted fluorine-containing Schiff bases starting from the drug isoniazid (isonicotinylhydrazide) were prepared and their structures were established by single-crystal X-ray diffraction. Also, four copper(II) complexes of these Schiff bases were synt...