MicroRNAs are 19-22 nt-long RNAs that regulate eukaryotic gene expression. They are processed from stem-loop containing precursor transcripts by RNAse III enzymes of the Dicer family. In this issue of the EMBO Journal, a study by Bologna and colleagues investigates the processing of two plant MIRNA families with unusually long precursors. Their findings suggest a non-canonical mode of biogenesi...

cell-type diversity. One particularly intriguing observamore carefully). How difficult would it be to recognize tion is that LIM-HD expression is dynamic (Tsuchida et your friends? Would inverted hors d’oeuvres pose a al., 1994; Appel et al., 1995; Sharma et al., 1998), raising challenge? If you selected an upside-down cheese blintz the possibility that precise temporal regulation of LIMwithout...

The schizophrenia deficit in facial emotion recognition could be accounted for by a deficit in processing the configural information of the face. The present experiment was designed to further test this hypothesis by studying the face-inversion effect in a facial emotion recognition task. The ability of 26 schizophrenic patients and 26 control participants to recognize facial emotions on uprigh...

Recently, Support Vector Regression (SVR) has been applied to financial time series prediction. Typical characteristics of financial time series are non-stationary and noisy in nature. The volatility, usually time-varying, of the time series is therefore some valuable information about the series. Previously, we had proposed to use the volatility to adaptively change the width of the margin of ...

Recently, Support Vector Regression (SVR) has been applied to financial time series prediction. Typical characteristics of financial time series are nonstationary and noisy in nature. The volatility, usually time-varying, of the time series therefore contains some valuable information about the series. Previously, we had proposed to use the volatility in the data to adaptively changing the widt...

Upside-down stomach represents a critical and rare manifestation of hiatal hernias. Here we report on a 60-year-old male patient who was admitted to our hospital with epileptic seizures and dehydration. Laboratory tests revealed severe metabolic alkalosis (pH 7.56) with low potassium (2.7 mmol/l), hypochloremia (<60 mmol/l), increased hematocrit (53%) and high levels of serum creatinine (651 µm...

What is the orientation of an object? A simple line has an axis of orientation. That line, turned upside-down, is indistinguishable from the original line. Thus, the possible orientations of a line range from 0 to 180 degrees. Most objects, however, have an axis and a polarity. A polar object, turned upside-down, looks upside-down. Accordingly, the orientations of a polar object range from 0 to...

OCR makes it possible for the user to edit or search the document’s contents. In this paper we describe a special water fill technique for detecting the upside down text document. Each character has a upside and downside filling capacities. A character may have two sides or one side filling capacity or zero filling capacity. The total upside and downside capacities for the scanned page calculat...