A 28-year-old man presented with a seven-day history of testicular pain. Physical examination revealed a mass in the lower pole of the left testis. This mass was a tumour suspect on scrotal ultrasound and MRI. Testicular tumour markers were negative. A radical orchidectomy was performed. Histologically, the diagnosis of polyarteritis nodosa (PAN) was made. Retrospectively, the diagnosis of PAN ...

The epididymis is the site where spermatozoa are matured and stored. After orchidectomy, this tissue loses up to 80% of its weight. In the prostate, androgen withdrawal by orchidectomy is associated with apoptotic cell death. The objective of the present study was to investigate whether apoptotic cell death is involved in the androgen-dependent weight loss found in the rat epididymis after orch...

AIMS To determine the role of polymerase chain reaction (PCR) based minimal residual disease (MRD) detection of leukaemia specific DNA in testicular relapse in childhood acute lymphoblastic leukaemia. METHODS DNA was obtained from archival testicular and bone marrow samples from boys with acute lymphoblastic leukaemia who relapsed in the testes. Overlapping DJH clone specific primers derived ...

The aim of the present study was to evaluate the effects of orchidectomy and subsequent chronic androgen administration on aortic media in male rabbits. Fifteen adult male rabbits were divided into orchidectomized (Orx), sham-operated controls (SO) and orchidectomized treated with testosterone dipropionate (Orx-TP). In all three groups, the mean area fraction of collagen in the outer half of th...

This study analyzes whether the release of nitric oxide (NO) and thromboxane A2 (TXA2) depends on the time lapsed since gonadal function is lost, and their correlation with the proliferation of vascular smooth muscle cells (VSMC) mediated by the epidermal growth factor receptor (EGFR). For this purpose, aortic and mesenteric artery segments from control and 6-weeks or 5-months orchidectomized r...

Submit Manuscript | http://medcraveonline.com reduced [3]. The reduction in fertility is documented in patients following orchidectomy with a contralateral viable testicle. In this case the contralateral testicle was atrophic following previous misdiagnosed torsion. Patients with severe testicular atrophy have undergone successful microdissection of sperm, in one study up to 56% of patients wit...

INTRODUCTION Testicular torsion may be an important cause of male infertility. We aimed to investigate the late hormonal function in patients with testicular ischemia/reperfusion injury of the testis after orchidectomy or detorsion. METHODS Twenty patients (mean age, 13.6 years) were prospectively evaluated at a mean of 5 years after testicular torsion. The serum follicle-stimulating hormone,...

Submit Manuscript | http://medcraveonline.com reduced [3]. The reduction in fertility is documented in patients following orchidectomy with a contralateral viable testicle. In this case the contralateral testicle was atrophic following previous misdiagnosed torsion. Patients with severe testicular atrophy have undergone successful microdissection of sperm, in one study up to 56% of patients wit...