The synthesis, computer modeling, and biological activity of an octawalled molecular umbrella short interfacing RNA (siRNA) conjugate is described. This molecular umbrella-siRNA conjugate exhibited mRNA knockdown activity in vitro in the absence of a transfection reagent. Evaluation of this molecular umbrella conjugate in vivo, using the rat eye via intravitreal injection, resulted in sequence ...

This paper indicate the importance of telecommunications supervision systems (TSS), integrating heterogeneous TSS into single system thru umbrella systems, introduces the structure, features, requirements of TSS and TSS related intelligent solutions. Keywords—Telecommunication, telecommunication supervision systems, umbrella systems

OBJECTIVE To demonstrate the safety and efficacy of intraoperative apical ventricular septal defect (VSD) closure using a modified Rashkind double umbrella. DESIGN Descriptive study of all patients in whom intraoperative device closure of apical VSDs was attempted. SETTING A tertiary referral centre. PATIENTS Four patients with an apical VSD requiring closure, during the period January 19...