high-performance liquid chromatography (hplc) methods employing ultraviolet (uv) detector are not sufficiently sensitive to measure the low plasma concentrations following single oral dose of imipramine. therefore, in the present study a simple, rapid and yet sensitive hplc method with uv detection was developed and validated for quantitation of imipramine in human plasma samples. an efficient ...

background : the aims of this study were evaluation of exposed to xylenes in low concentration and compare urinary level of methyl hippuric acid in taxi drivers and petrol stations workers in west of iran. methods: this observation study was carried out on samples of the exposed men to xylenes in two occupational groups in hamadan city (west of iran) from march 2003 to march 2004. subjects incl...

tetracyclines (tcs) are broad-spectrum antibiotics that are used widely in veterinary medicine. the present study was carried out to trace the residues of oxytetracycline (otc) and tetracycline (tc) in pasteurized milk that is marketed in tehran with the use of a high performance liquid chromatography (hplc). ninety milk samples were collected during five sequential days from the products of si...

a rapid, simple and sensitive high-performance liquid chromatography method was developed for determination of ciprofloxacin in plasma by means of ultraviolet detection. ofloxacin was used as an internal standard and separation carried on a novapak c18 column using a mobile phase of 0.01 m phosphate buffer (ph =2.6): methanol (82: 18 v/v). extraction of drug was performed from plasma by liquid-...

The present study was designed to develop a simple, validated liquid chromatographic method for the analysis of azithromycin in bulk and pharmaceutical dosage forms using ultraviolet detector. The best stationary phase was determined as C18 column, 5 μm, 250 mm × 4.6 mm. Mobile phase was optimized to obtain a fast and selective separation of the drug. Flow rate was 1.5 mL/min, Wavelength was se...

The following report describes the analysis for finding the speed of an extensive air shower produced by an ulta-high energy cosmic ray. Not only will this analysis be useful in measring the speed of cosmic ray showers but also it can help in correcting a bias in the detection instrumentation. As cosmic rays enter Earth’s upper atmosphere, they interact with nuclei, creating secondary particles...

Sorbitol and glycerol, along with other inactive ingredients such as preservatives and dyes, are commonly used in various pharmaceutical and personal care products. To accurately assess the effectiveness of various formulations containing sorbitol and/or glycerol, their quantitative determination is essential. In the current study, two types of detectors (a Varian evaporative light scattering d...

A flow-electrolytic cell that consists of a bare gold wire or of different thiol-compound-modified gold electrodes (such as 2,4-thiazolidinedione, 2-mercapto-5-thiazoline, 2-mercaptothiazoline, l-cysteine, thioglycolic acid) was designed to be used in a voltammetric detector to identify l-selenomethionine and Se-methylseleno-l-cysteine using high-performance liquid chromatography. Both l-seleno...

Lithol Rubine B (LRB; the disodium salt of 3-hydroxy-4-[(4-methyl-2-sulfophenyl) azo]-2-naphthalenecarboxylic acid) was detected using high-performance liquid chromatography with an electrochemical (antimony film on silver) detector (HPLC-ECD). For direct current (DC) mode, with the current at a constant potential, and measurements with suitable experimental parameters, a linear concentration f...