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OBJECTIVES Ulcerative colitis is an inflammatory bowel disease that rarely exists in isolation in affected patients. We examined the association of ulcerative colitis and International Classification of Diseases mental disorder, as well as the temporal comorbidity of three broad International Classification of Diseases groupings of mental disorders in patients with ulcerative colitis to determi...

background: the incidence of ulcerative colitis (uc) is rising in populations with western-style diet, rich in fat and protein, and low in fruits and vegetables. in the present study, we aimed to evaluate the association between dietary protein intakes and the risk of developing incident uc.   methods : sixty two cases of uc and 124 controls were studied using country-specific food frequency qu...

The acute effects of single pharmacological doses of glucocorticoid hormones on net electrolyte and water transport and electrical potential difference (pd) in the rectum was studied in control subjects and in patients with either active or inactive ulcerative colitis, using a dialysis technique. Compared with 17 control subjects, nine patients with active ulcerative colitis exhibited marked de...

Background: Inflammatory bowel disease includes ulcerative colitis and Crohn’s disease. Immunomodulatory effects of vitamin D have been linked with autoimmune diseases such as inflammatory bowel disease. Procalcitonin as a marker of inflammation, has been proposed for bacterial infections. Objectives: The aim of our study was to investigate the relationship between serum level of vitamin D and ...

Pemphigus vulgaris is an autoimmune bullous disorder characterized by the production of autoantibodies against the intercellular space of the epithelium. It has rarely been reported in association with inflammatory bowel disease. Ulcerative colitis is one of the forms of inflammatory bowel disease. A 62-year-old woman who had been treated for ulcerative colitis for 16 years developed pruritic b...

were measured in 15 patients with ulcerative colitis, 15 patients with Crohn's disease, and 12 normal control subjects. Diminished reactivity to DNCB was demonstrated in 87% of patients with Crohn's disease (p < 0 001) and in 53% with ulcerative colitis (p < 0 02), as compared with only 8-5 % of controls; anergy was more frequent in Crohn's disease than in ulcerative colitis (p < 0 05). Levels ...

BACKGROUND The pathogenesis of ulcerative colitis is unclear, but cytotoxic T lymphocytes infiltrating the mucosa have been implicated in mucosal damage. The Fas ligand (FasL), expressed on cytotoxic T lymphocytes, induces apoptosis in cells expressing Fas. AIM To analyse FasL expression in affected colonic mucosa to ascertain Fas-FasL interaction in ulcerative colitis. METHODS FasL mRNA wa...