Imbalance between exogenous damaging agents and protective factors in the gastro-duodenum tract can lead to peptic ulcer disease. Herbal medicines could be an effective treatment human gastric ulcers. This study aimed investigate effect of AGAR-HP hard capsules on cysteamine-induced gastric-duodenal ulcers experimental rats. The animals were divided into five groups: Group 1 (control) group 2 (...

OBJECTIVE To evaluate the possible antiulcer effect of the African garden egg, Solanum aethiopicum (S. aethiopicum) (a domestic vegetable) experimentally in rats. METHODS A methanol extract of the plant fruit was prepared by maceration. Twenty five overnight fasted rats for each model were divided randomly into five groups of five rats. Groups 1, 2, 3, 4 and 5 received normal saline, extract ...

BACKGROUND Pressure ulcers, which are localised injury to the skin, or underlying tissue or both, occur when people are unable to reposition themselves to relieve pressure on bony prominences. Pressure ulcers are often difficult to heal, painful and impact negatively on the individual's quality of life. The cost implications of pressure ulcer treatment are considerable, compounding the challeng...

For more than a century, peptic ulcer disease has been a major cause of morbidity and mortality. In the early part of the 20th century, when stress and diet were judged to be important pathogenetic factors for peptic ulceration, patients with peptic ulcers were treated with hospitalization, bed rest, and the prescription of “bland” diets. By the 1950s, investigators and clinicians had focused t...

Peptic ulcer bleeding is associated with substantial morbidity and mortality. The goals of management are to control any active bleeding and prevent re-bleeding and then to heal the ulcer and prevent its recurrence. Initial management strategies are guided by the patient's clinical condition and endoscopic findings. Thus, treatment may consist of endoscopic and medical therapy and, sometimes, s...

Objective: Nelumbo nucifera Gaertn. (Nymphaeceae) is a well known aquatic herb which has been extensively used traditionally for the treatment of different diseases. Therefore present study was designed to evaluate the anti-ulcer activity of methanolic extract of Nelumbo nucifera Gaertn. (Nymphaeceae) stalks. Methods: Anti-ulcer activity of methanolic extract of Nelumbo nucifera (100 mg/kg and ...