BACKGROUND Because of its non-electrostatic properties the metal Nebuchamber (NC) valved holding chamber (VHC) delivers a greater mass of aerosol to the mouth than the polypropylene Aerochamber (AC) VHC. Delivery of more aerosol to the lungs may also increase systemic absorption of inhaled corticosteroids (ICS) and hypothalamo-pituitary-adrenal (HPA) suppression. METHODS Thirty children (mean...

The ubiquitous fashionable computer(UFC), introduced in this paper, is a wearable computer that exploits ubiquitous computing environment. In the ubiquitous environment, wearable computing systems integrate various types of devices, like communication interfaces and user interfaces to get services in any time and any where and facilitate the computing system without any burdensomeness. In addit...

CONTEXT Late-night salivary cortisol (LNSC) is well-validated in the diagnosis of Cushing's disease (CD). The accuracy of LNSC during follow-up of patients undergoing transsphenoidal surgery (TSS) has not been fully characterized. OBJECTIVES We examined the accuracy of LNSC in establishing remission and identifying recurrence in postoperative patients with CD. DESIGN This is a retrospective...

Cushing's disease is Cushing's syndrome caused by an adrenocorticotropic hormone-secreting pituitary adenoma and, in the absence of adequate treatment, can be fatal. Cushing's disease represents an unmet medical need, with no approved medical therapies. Pasireotide is a novel multi-receptor-targeted somatostatin analogue with high affinity for sst(1,2,3) and sst(5). Compared with octreotide, pa...

BACKGROUND A study was undertaken to assess the function of the hypothalamic-pituitary-adrenal axis (HPA) in a group of asthmatic children before and after treatment with inhaled corticosteroids. METHODS Thirty prepubertal patients of mean (SD) age 6.7 (1.8) years were treated with inhaled corticosteroids. All children underwent a corticotrophin releasing hormone (CRH) test with evaluation of...

BACKGROUND Investigations on the relationship between obesity, binge eating and the function of hypothalamic-pituitary-adrenal (HPA) axis have led to inconsistent results. General psychopathology affects HPA axis function. The present study aims to examine correlations between binge eating, general psychopathology and HPA axis function in obese binge eaters. METHODS Twenty-four hour urinary f...

The interactive ubiquitous computing project, U-TOPIA, explores new possibilities for people working together in technology-rich spaces. Ubiquitous fashionable computers have more to do with form factor and usability than with computing. This paper focuses on our effort to overcome the challenges in a limited user interface of a wearable computer by providing a new interface, called Ubiquitous ...

The objective of this study was to determine the level of adoption within the Algerian poultry farms (broiler chickens, laying hens) of a range of standard biosecurity practices (isolation, traffic control, decontamination, vaccination...). Quantitative and qualitative evaluation of the biosecurity in the poultry houses has been analyzed thanks using method developed by the French Food Safety A...

CONTEXT The diagnosis of Cushing's syndrome (CS) requires the use of tests of unregulated hypercortisolism that have unclear accuracy. OBJECTIVE Our objective was to summarize evidence on the accuracy of common tests for diagnosing CS. DATA SOURCES We searched electronic databases (MEDLINE, EMBASE, Web of Science, Scopus, and citation search for key articles) from 1975 through September 200...