Genome-wide association studies (GWAS) facilitate largescale identification of genomic variants that are associated with complex traits. However, susceptibility loci identified by GWAS so far generally account for a limited fraction of the genotypic variation in patient populations. Predictive models based on identified loci also have modest success in risk assessment and therefore are of limit...

On-going research aims at answering the question, which satiety signal is the most potent or which combination of satiety signals is the most potent to stop eating. There is also an aim at finding certain food items or food additives that could be used to specifically reduce food intake therapeutically. Therapeutic attempts to normalize body weight and glycaemia with single agents alone have ge...

The study was designed to find out the relation between lipid peroxidation, lipoprotein levels to severity and complication of diabetes mellitus. Degree of lipid peroxidation was measured in terms of malondialdehyde (MDA) along with antioxidants, lipid profile and blood glucose in diabetes mellitus. Total 100 human subjects, out of which 50 healthy individuals of age group (50-70years) were tak...

BACKGROUND Diabetes is associated with cognitive decline or dementia. The purpose of this study was to assess the executive functions and information processing in patients with type 2diabetes in comparison to pre-diabetic patients and normal subjects in Endocrine and Metabolism Research Center of Isfahan City from April to July 2011. METHODS The sample consisted of 32 patients with type 2 di...

Objective: The goal of this research was to determine the influence of 4 weeks aerobic training on gene expression of tumor necrosis factor alpha (TNF-α), hypoxia-inducible factor-1 alpha (HIF-1α) and vascular endothelial growth factor (VEGF) in the cardiac tissue of diabetic rats. Materials and Methods: In an experimental study, 30 male wistar rats were partitioned into three groups (n=10), d...