A primate lymphotropic lentivirus was isolated on the human T-cell line HuT 78 after cocultivation of a lymph node from a pig-tailed macaque (Macaca nemestrina) that had died with malignant lymphoma. This isolate, originally designated M. nemestrina immunodeficiency virus (MnIV) and now classified as simian immunodeficiency virus (SIV/Mne), was inoculated intravenously into three juvenile rhesu...

Let Sn = ξ1 + · · · + ξn be a sum of i.i.d. non-negative random variables, S0 = 0. We study the asymptotic behaviour of the probability P{X(T ) > n}, n→∞, where X(t) = max{n ≥ 0 : Sn ≤ t}, t ≥ 0, is the corresponding renewal process. The stopping time T has a heavy-tailed distribution and is independent of X(t). We treat two different approaches to the study: via the law of large numbers and by...

The aim of the present study was to undertake a longitudinal study of systolic and diastolic cardiac function during normal pregnancy. At a median of 16 weeks of gestation, 100 primiparous women underwent echocardiography, including tissue Doppler imaging, determining left ventricular mass, cardiac output, systolic and diastolic velocities, and wall stress. A total of 32 were assessed again at ...

BACKGROUND The objective of this study was to evaluate the expression levels of glycolytic markers, especially hexokinase-2 (HK2), using a three-dimensional multicellular spheroid model of human ovarian adenocarcinoma (SKOV-3) cells and to develop an epidermal growth factor receptor-targeted liposomal formulation for improving inhibition of HK2 and the cytotoxicity of 3-bromopyruvate (3-BPA). ...

The lesser short-tailed bat (Mystacina t. tuberculata) has been found in 18 locations in indigenous forest in North Island since 1961, mainly in Northland kauri forest (including Little Barrier Island), on the volcanic plateau (including Tongariro National Park), Urewera National Park and in Tararua Range. In South Island this bat has only been reported once since 1961, in North West Nelson For...

BACKGROUND/AIMS To determine the impact of prosthetic replacement of the ocular surface ecosystem (PROSE) treatment at 5 years. METHODS Retrospective review of clinical, manufacturing and quality databases at the Boston Foundation for Sight. RESULTS 121 patients who completed treatment and had 5-year follow-up data were identified from a cohort of patients (n=199) seen in consultation for P...

In this paper we consider a single-server queue with Lévy input, and in particular its workload process (Q(t)), for t > 0, with a focus on the correlation structure. With the correlation function defined as r(t) := Cov(Q(0),Q(t))/Var Q(0) (assuming that the workload process is in stationarity at time 0), we first determine its transform. This expression allows us to prove that r(.) is positive,...

The increasing prevalence of human immunodeficiency virus type 1 (HIV-1) subtype C infection worldwide calls for efforts to develop a relevant animal model for evaluating strategies against the transmission of the virus. A chimeric simian/human immunodeficiency virus (SHIV), SHIV(CHN19), was generated with a primary, non-syncytium-inducing HIV-1 subtype C envelope from a Chinese strain in the b...

This study aims to determine the effectiveness of learning model Discovery Learning and Inquiry on thematic outcomes fourth grade elementary school students. research is a quasi-experimental using design that Noneguivalent Control Group Design. The population in this were students Merbabu cluster. Determination sample by non-probability sampling technique purposive type. used was SD Negeri Kope...

The purpose of this research is to determine whether using the IMPROVE learning approach can improve students' ability think critically mathematically. This experimental used a pretest-posttest control group design. involved all students in class XI MIPA SMA Negeri 1 Peukan Baro. Two classes, and 2, were selected as samples. study uses questions test mathematical critical thinking skills. After...