background: the objective of this study is to optimize the effective dose of heparin and ligustrazine hydrochloride injection (lhi) for drug combination. materials and methods: the animal clinical study of lhi was performed by the rat’s model of induced arteriovenous shunt thrombosis. experimental animals were grouped into several groups and separately treated with both lhi (20, 40, 80 mg/kg, i...

background: designing intervention based on health-care settings resources and patient acceptability is potentially important in the prevention of high blood pressure (bp) and other risk factors of cardiovascular disease. to explain a multicenter randomized controlled trial that is designed to examine the effects of the multicomponent lifestyle modification program on bp. materials and methods:...

background: the aim of this study was to detect prognostic factors in recurrent breast cancer metastasis. materials and methods: th is retrospective cohort study employed data from 996 breast cancer patients of isfahan seyed-o-shohada research center from 1998 to 2010. stratifi ed cox proportional hazards model, marginal approach, was used to evaluate the prognostic value of estrogen receptor, ...

homogeneously staining regions (hsr) or double minute chromosomes (dmin) are autonomously replicating extra-chromosomal elements that are frequently associated with gene amplifi cation in a variety of cancers. the diagnosis of leukemia patients was based on characterization of the leukemic cells obtained from bone marrow cytogenetics. this study report two cases, one with acute myeloblastic leu...

bronchial leiomyoma is extremely rare. to date less than 60 cases have been reported in the world literature. the presented case here is a 30 year old woman who had been treated for bronchial asthma for several years. her chest radiograph showed bulluos emphysematous changes in the right lung and computer tomography scan found the tumor in the right main bronchus near carina. diagnosis was made...