نتایج جستجو برای: tt virus
تعداد نتایج: 407242 فیلتر نتایج به سال:
Interferon lambda 4 protein can be generated in IFNL4-ΔG carriers but not IFNL4-TT homozygotes. We studied 890 anti-hepatitis C virus (HCV)-positive participants in the Women's Interagency HIV Study. Among blacks (n = 555), HCV was more often cleared for those with genotype IFNL4-TT/TT (32.6%; odds ratio [OR], 3.59; P = 3.3 × 10(-5)) than IFNL4-TT/ΔG (11.3%; OR, 0.95; P = .86) or IFNL4-ΔG/ΔG (1...
conclusions there is an as yet unexplained association between hcv and host parameters with unknown mechanisms in patients with chronic hcv infection. the assessments of core aa 70 substitution and polymorphisms near the ifnl3 gene could offer promising steps to improve the management of patients with hcv. background molecular studies have demonstrated that the hepatitis c virus (hcv) genotype ...
A novel nontoxic form of chimeric mucosal adjuvant that combines the A subunit of mutant cholera toxin E112K with the pentameric B subunit of heat-labile enterotoxin from enterotoxigenic Escherichia coli was constructed by use of the Brevibacillus choshinensis expression system (mCTA/LTB). Nasal immunization of mice with tetanus toxoid (TT) plus mCTA/LTB elicited significant TT-specific immunog...
Approximately one-third of the individuals infected with human immunodeficiency virus type 1 (HIV-1) are co-infected with hepatitis C virus (HCV). Co-infected patients have an increased risk for developing end-stage liver diseases. Variants upstream of the IFNL3 gene have been associated with spontaneous and treatment-induced clearance of HCV infection. Recently, a novel polymorphism was discov...
برنامه های درسی یکی از مهمترین عناصر و عوامل تاثیرگذار در تعیین میزان موفقیت و شکست نظام های آموزش عالی هستند. با توجه به تغییر و تحول سریع جهان و مطرح شدن مسایل و نیازهای جدید برای جوامع، برنامه های درسی آموزش عالی باید ارزشیابی و بازنگری شوند تا براساس اقتضائات زمانی و مکانی طراحی و تدوین شوند. یکی از رویکردهای برنامه درسی که در نیم قرن اخیر تداوم داشته و بطور روزافزون در سرتاسر جهان رو به گس...
Abstract Background Interferon (IFN)- ?4, a type III IFN, production is controlled by dinucleotide frameshift variant (rs368234815-dG/TT) within the first exon of IFNL4 gene. Carriers -dG allele but not -TT are able to produce IFN-?4 protein. Patients with hepatitis C virus that do protein have higher rates viral clearance suggesting potential inhibitory role in liver-tropic infections. Methods...
The results of this study show that donor-derived immunity can be detected and persists in long-term survivors with and without chronic graft-v-host disease (GVHD) after human marrow grafting. Seventy-one marrow recipients (60 long-term and 11 short-term survivors) were studied for the presence of specific serum IgG antibodies to tetanus toxoid (TT), and 46 marrow recipients (35 long-term and 1...
Abstract Good tools can bring mechanical verification to programs written in mainstream functional languages. We use hs-to-coq translate significant portions of Haskell’s containers library into Coq, and verify it against specifications that we derive from a variety sources including type class laws, the library’s test suite, interfaces Coq’s standard library. Our work shows is feasible mature,...
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