Troponins are the preferred markers for risk stratification of patients with acute coronary syndromes and for making the diagnosis of myocardial infarction (MI). They guide the selection of antithrombotic therapy and selection of an invasive strategy. They are also indicative of myocyte necrosis in a number of other clinical situations such as pulmonary embolism, myopericarditis, heart failure,...

background: serum troponin elevation, characteristic of ischemic myocardial injury, has been observed in some acute ischemic stroke (ais) patients. its cause and significance are still controversial. the purpose of this study is to find determinants of troponin elevation and its relationship with stroke severity and location. methods: between january 2013 and august 2013, 114 consecutive ais pa...

Objective: Acute rheumatic fever is still one of the leading causes of mortality and morbidity due to heart disease in developing countries. Carditis is the most important manifestation of the disease and there are still difficulties in diagnosis. Cardiac troponin-T measurement has been found to be valuable in recognition of cardiac injury in various disease states. We investigated the cardiac ...

Troponin I is the actomyosin ATPase inhibitory subunit present in the thin filament regulatory complex. The complete amino acid sequence of crayfish tail muscle troponin I has been determined. The protein is composed of 201 amino acid residues and has a molecular weight of 23,547. The N terminus is blocked, likely by an acetyl group. Crayfish troponin I shows a rather low (20-25%) sequence iden...

STUDY OBJECTIVE Myocardial contusion may induce life-threatening complications, but its diagnosis is difficult. Circulating cardiac troponin T is considered a highly sensitive and specific marker of myocardial cell injury. We investigate the value of cardiac troponin T measurement in the diagnosis of myocardial contusion. DESIGN Prospective study. SETTING Level 1 trauma center. METHODS We...

BACKGROUND High-sensitivity cardiac troponin assays will augment the frequency of increased results, making important the determination of reference change values to distinguish acute from chronic increases. We assessed short- and long-term biological variability of cardiac troponin T (cTnT) in healthy subjects with a novel high-sensitivity (hs) assay. METHODS We collected blood from 20 healt...

conclusions in patients without clear signs of myocardial infarction, even mild co poisoning was associated with quantifiable circulating levels of hs-ctnt when tnt was measured using a highly sensitive assay in the current study patients. plasma levels of the hs-tnt and ck-mb assays were not correlated with the cohb levels in the current study patients. results the mean age of the patients was...

Objective: To examine the long term prognostic characteristics of troponin T testing and continuous multilead ST segment monitoring in combination with clinical and 12 lead ECG risk indicators in patients with acute coronary syndromes (ACS). Patients and design: Patients with suspected ACS (n = 213) were studied. Troponin T was analysed in blood samples collected during the first 12 hours after...

BACKGROUND The prognostic importance of elevated cardiac enzymes after elective percutaneous coronary intervention has been debated. Therefore, we performed a prospective observational study to evaluate the prognostic value of postprocedural rise of troponin T and creatine kinase. METHODS Troponin T (cut-off value 0.05 ng/ml) and creatine kinase (cut-off value 180 IU/l with muscle-brain fract...