Phytochemical study of the ethanol extract of the seeds of Aesculus chinensis led to the isolation of a new triterpenoid saponin (6), together with five known triterpenoid saponins (1-5). The structure of the new compound was elucidated on the basis of spectral data to be 21,28-di-O-acetylprotoaescigenin-3-O-[beta-D-glucopyranosyl(1-2)][beta-D-glucopyranosyl(1-4)]-beta-D-glucopyranosiduronic ac...

Six new triterpenoid saponins, psychotrianosides A-F (1-6), and two known triterpenoid saponins, psychotrianoside G (7) and ardisianoside D (8), were isolated from Psychotria sp. Their structures were determined mainly by spectroscopic methods. The cytotoxic activities of 1-8 against five human cancer cell lines (MDA-MB-231, MCF-7, MCF-7/ADM, HepG2, and HepG2/ADM) are reported for the first tim...

Salak termasuk famili Arecaceae yang merupakan tanaman asli Indonesia, salak dapat diolah menjadi produk makanan seperti keripik salak, kopi biji dan obat tradisional. Berdasarkan penelitian sebelumnya, mengandung senyawa metabolit sekunder berupa alkaloid, flavonoid, steroid/triterpenoid tanin. Kebaruan dalam ini karena menganalisis kromatografi lapis tipis aktivitas antimikroba ekstra n-heksa...

Three new triterpenoid saponins, named celosin E (1), celosin F (2) and celosin G (3), together with a known compound cristatain (4), were isolated from the seeds of Celosia argentea L. (Amaranthaceae). All the isolated compounds were obtained for the first time from this plant. The structures of new compounds were characterized on the basis of extensive NMR experiments and mass spectrometry da...

Background: Hylomecon japonica, a plant of the Papaveraceae family which is well-known for the alkaloids they produce, is a perennial plant widely distributed in the northeast, central and east regions of China. Although a variety of chemical constituents, including alkaloids, flavonoids, and megastigmoids, have been isolated from H. japonica, the investigation of saponins in H. japonica has no...

Naturally occurring triterpenoid compounds have long been used as anti-inflammatory, antimalarial, and insecticidal agents. It has become evident that some of the natural or synthetic triterpenoids have promising clinical potential as both a therapeutic and chemopreventive agent for cancer. However, the molecular basis for the antitumor activity of triterpenoid has yet to be defined. In this st...

Abstract Two new triterpenoid saponins, named giganteasaponin 5 and giganteasaponin 6, were isolated from the aboveground parts of Solidago gigantea and were defined to be 3-O-[ -D-Apio-D-furanosyl-(1 3)-D-glucopyranosyl-(1 3)-D-glucopyranosyl]-28-O { -L-rhamnopyranosyl-(1 3)-D-xylopyranosyl-(1 4)[ -D-xylopyranosyl-(1 3)]-L-rhamnopyranosyl-(1 2) [ -L-rhamnopyranosyl-(1 3)]-Dxylopyranosyl}-Bayog...