نتایج جستجو برای: triclosan

تعداد نتایج: 2220  

Journal: :Antimicrobial agents and chemotherapy 2008
David J Stickler Gwennan L Jones

Clinical isolates of Proteus mirabilis causing catheter encrustation and blockage are susceptible to the biocide triclosan (MICs of 0.2 mg/liter). Studies with laboratory models of the bladder have demonstrated that the inflation of catheter retention balloons with triclosan solutions rather than water results in the diffusion of triclosan from the balloons into the surrounding urine and the in...

Journal: :Antimicrobial agents and chemotherapy 2002
Frank Fan Kang Yan Nicola G Wallis Shannon Reed Terrance D Moore Stephen F Rittenhouse Walter E DeWolf Jianzhong Huang Damien McDevitt William H Miller Mark A Seefeld Kenneth A Newlander Dalia R Jakas Martha S Head David J Payne

The MICs of triclosan for 31 clinical isolates of Staphylococcus aureus were 0.016 micro g/ml (24 strains), 1 to 2 micro g/ml (6 strains), and 0.25 micro g/ml (1 strain). All the strains for which triclosan MICs were elevated (>0.016 micro g/ml) showed three- to fivefold increases in their levels of enoyl-acyl carrier protein (ACP) reductase (FabI) production. Furthermore, strains for which tri...

Journal: :The Journal of biological chemistry 1999
R J Heath J R Rubin D R Holland E Zhang M E Snow C O Rock

Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Resistance to triclosan in Escherichia coli is acquired through a missense mutation in the fabI gene that leads to the expression of FabI[G93V]. The specific activity and substrate affinities of FabI[G93V] are similar to FabI. Two different bind...

Journal: :Aquatic toxicology 2016
Joseph G Schnitzler Bruno Frédérich Mélanie Dussenne Peter H M Klaren Frédéric Silvestre Krishna Das

Thyroid hormones are critically involved in somatic growth, development and metamorphosis of vertebrates. The structural similarity between thyroid hormones and triclosan, an antimicrobial compound widely employed in consumer personal care products, suggests triclosan can have adverse effects on the thyroid system. The sheepshead minnow, Cyprinodon variegatus, is now used in ecotoxicological st...

Journal: :Veterinary microbiology 2005
Kim Oren Gradel Luke Randall Anthony R Sayers Robert H Davies

A putative link between Salmonella persistence in the agricultural sector and resistance to disinfectants has been sparsely investigated. Therefore, minimum inhibitory concentration (MIC) tests against five disinfectants commonly used in poultry premises (formaldehyde, glutaraldehyde/benzalkonium chloride compound, oxidising compound, tar oil phenol, iodophor) were performed on 286 Salmonella i...

Journal: :The Science of the total environment 2009
Thomas J Leiker Sonja R Abney Steven L Goodbred Michael R Rosen

Methyl triclosan and four halogenated analogues have been identified in extracts of individual whole-body male carp (Cyprinus carpio) tissue that were collected from Las Vegas Bay, Nevada, and Semipermeable Membrane Devices (SPMD) that were deployed in Las Vegas Wash, Nevada. Methyl triclosan is believed to be the microbially methylated product of the antibacterial agent triclosan (2, 4, 4'-tri...

Journal: :The Journal of antimicrobial chemotherapy 2006
G Ll Jones C T Muller M O'Reilly D J Stickler

OBJECTIVES To examine (i) the effect of triclosan on the formation of catheter biofilms by urinary tract pathogens and (ii) the diffusion of triclosan through the retention balloons of urinary catheters. METHODS Models of the catheterized bladder were infected with eight different urinary tract pathogens and the effect of triclosan on biofilm formation was assessed by determining the numbers ...

Journal: :The Journal of antimicrobial chemotherapy 2005
Margarita Gomez Escalada J L Harwood J-Y Maillard D Ochs

OBJECTIVES To assess the effect of triclosan on fatty acid synthesis and to relate the inhibition of enoyl reductase to bacterial viability. METHODS The effect of triclosan on fatty acid synthesis in a triclosan-resistant Escherichia coli and its sensitive counterpart and in Pseudomonas aeruginosa was investigated by measuring acetate incorporation into total lipid followed by analysis of fat...

Journal: :Environmental toxicology and chemistry 2016
Tim Verslycke David B Mayfield Jade A Tabony Marie Capdevielle Brian Slezak

Triclosan (5-chloro-2-[2,4-dichlorophenoxy]-phenol) is an antimicrobial agent found in a variety of pharmaceutical and personal care products. Numerous studies have examined the occurrence and environmental fate of triclosan in wastewater, biosolids, biosolids-amended soils, and plants and organisms exposed to biosolid-amended soils. Triclosan has a propensity to adhere to organic carbon in bio...

ژورنال: سلامت و محیط زیست 2018

Background and Objective: Triclosan is one of the substances as anti-microbial that is used in many of these pharmaceutical products. This compound can affect human such as reduction of thyroid hormone levels, antibiotic resistant, and increasing skin cancer. This study evaluated the performance nanophotocatalysis process UV/Xe/TiO2-GO on triclosan removal from aqueous solutions. Materials and...

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