Synthesis of several pryrazolo[4,3-e][1,2,4]-triazines is described. The absorption spectrum of some 5-substituted derivatives was found to extend to the visible region. These compounds were found to inhibit some enzymes of purine metabolism, like xanthine oxidase or bacterial purine-nucleoside phosphorylase with Ki values in the 10(-3) -10(-5) M range.

Sym-triazines have been documented for their antitumor, antimicrobial and anti-cancer actions. The present work aims to derive a variety of 1,3,5-triaryl-1,3,5-hexahydrotriazine using ultrasound assisted reactions from the reactions of aryl amines with aqueous formaldehyde. Furthermore, a special study on the different solvents and revealed that mixture of water and ethanol was found to be the ...

In the title compound, C(5)H(9)N(5)O(5), prepared from hexa-mine by acetyl-ation and nitration, the triazine ring adopts a chair conformation with all three substituent groups lying on the same side of the ring.