نتایج جستجو برای: triadic componential framework tcf
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Psychological theories of emotion have often defined an as simultaneous changes in several mental and bodily components. In addition, appraisal assume that component elicits the other components (e.g., motivational, behavioural, experiential). Neither componential definition nor theory been systematically translated to paradigms for induction, many which rely on passive induction without a clea...
Triadic relationships are accepted to play a key role in the dynamics of social and political networks. Building on insights gleaned from balance theory in social network studies and from Boltzmann-Gibbs statistical physics, we propose a model to quantitatively capture the dynamics of the four types of triadic relationships in a network. Central to our model are the triads' incidence rates and ...
E ective Static Debugging via Componential Set Based Analysis
Trichlorfon (TCF) is a widely used broad-spectrum agricultural organophosphate (OP) pesticide. Few studies have evaluated the effects of TCF on reproductive toxicity after low-level exposure, especially after long-term exposure. This study assessed the direct effects of TCF on estrous cycle, oocyte maturation in female mice, and developmental outcome in nearterm fetuses after 30 consecutive day...
We have analyzed the teleconnection of total cloud fraction (TCF) with global sea surface temperature (SST) in multi-model ensembles (MME) fifth and sixth Coupled Model Intercomparison Projects (CMIP5 CMIP6). CMIP6-MME has a more robust realistic (TCF SST) pattern over extra-tropics (R ~ 0.43) North Atlantic 0.39) region, which turn resulted an improvement rainfall bias Asian summer monsoon (AS...
Overwhelming activation of IL-17, a gene involved in inflammation, leads to exaggerated Th17 responses associated with numerous autoimmune conditions, such as experimental autoimmune encephalomyelitis (EAE). Here we show that TCF-1 is a critical factor to repress IL-17 gene locus by chromatin modifications during T cell development. Deletion of TCF-1 resulted in increased IL-17 gene expression ...
CD3-e gene expression is confined to the T cell lineage. We have recently identified and cloned a human transcription factor, TCF-1, that binds to a functional element in the T lymphocyte-specific enhancer of CD3-e . In a panel of human cell lines, TCF-1 expression was restricted to T lineage cells . TCF-1 belonged to a novel family of genes that contain the so-called high mobility group 1 (HMG...
The Tcf family of transcription factors, in association with beta-catenin, mediate Wnt signaling by transactivating downstream target genes. Given the function of wnt genes in neural development and organogenesis, Tcf transcription factors must be integral to the development of many embryonic tissues. In fact, the role of Tcf genes in axis formation in Xenopus and in segment polarity in Drosoph...
OBJECTIVE The purpose of the present study was to determine the prevalence and incidence of virological triple drug-class failure (TCF) and to summarize the clinical outcome for patients who started receiving highly active antiretroviral therapy (HAART). METHODS The present study is an observational longitudinal study of 3496 treatment-experienced (TE) and treatment-naive (TN) patients monito...
By interacting with MHC class II molecules, CD4 facilitates lineage development as well as activation of Th cells. Expression of physiological levels of CD4 requires a proximal CD4 enhancer to stimulate basic CD4 promoter activity. T cell factor (TCF)-1/beta-catenin pathway has previously been shown to regulate thymocyte survival via up-regulating antiapoptotic molecule Bcl-xL. By both loss and...
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