conclusions affordable new hcv treatment regimens are available in iran, providing an opportunity for hcv elimination. recommendations provided in this current national guideline can facilitate evidence-based management of hcv infection. results pegylated interferon alpha (pegifn), ribavirin (rbv), sofosbuvir (sof), ledipasvir (ldv) and daclatasvir (dcv) are currently available in iran. pre-tre...

The international data have indicated a growing trend of alcohol use worldwide during recent years. Although alcohol use is against cultural norms and religious law in Iran, anecdotal reports from substance abuse treatment providers show that there is demand for alcohol treatment in the country. A recent national report also documented alcohol use disorders in Iran. Development and implementati...

The KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of CKD-MBD represents a selective update of the prior CKD-MBD Guideline published in 2009. This update, along with the 2009 publication, is intended to assist the practitioner caring for adults and children with chronic kidney disease (CKD), those on chronic dialysis therapy, or individual...

Background: Diabetic foot infection is the most common complication of diabetic foot ulcer (DFU) leading to amputation. The treatment requires special attention to disease conditions, proper diagnosis, appropriate sampling for cultures, careful selection of antibiotics, rapid determination of the patient’s need for surgical intervention, and wound care. Clearly a systematic approach or, if poss...

Electrolyte disorders are common and often challenging in terms of differential diagnosis and appropriate treatment. To facilitate this, the first Dutch guideline was developed in 2005, which focused on hypernatraemia, hyponatraemia, hyperkalaemia, and hypokalaemia. This guideline was recently revised. Here, we summarise the key points of the revised guideline, including the major complications...

OBJECTIVES To assess variation in and determinants of rheumatologist guideline adherence in patients with rheumatoid arthritis (RA), in daily practice. METHODS In this retrospective observational study, guideline adherence in the first year of treatment was assessed for 7 predefined parameters on diagnostics, treatment and follow-up in all adult patients with RA with a first outpatient clinic...

- A delegation of 6 pediatric orthopedic surgeons from the Dutch Orthopedic Association (NOV) and 2 members of the board of the Dutch Parents' Association for children with clubfoot created the guideline "The diagnosis and treatment of primary idiopathic clubfeet" between April 2011 and February 2014. The development of the guideline was supported by a professional methodologist from the Dutch ...

The National Kidney Foundation-Kidney Disease Outcomes Quality Initiative (NKF-KDOQI) guideline for management of dyslipidemia in chronic kidney disease (CKD) was published in 2003. Since then, considerable evidence, including randomized controlled trials of statin therapy in adults with CKD, has helped better define medical treatments for dyslipidemia. In light of the new evidence, KDIGO (Kidn...

The ’2012 European guideline on the diagnosis and treatment of gonorrhoea in adults’ was launched on November 15, 2012 on the website for European STI Guidelines and is also accepted for publication in International Journal of STD & AIDS [1]. The newly launched guideline, an updated version of the 2009 European (IUSTI/WHO) guideline on the diagnosis and treatment of gonorrhoea in adults [2], pr...

The guideline of the Korean College of Helicobacter and Upper Gastrointestinal Research group for Helicobacter pylori infection was first produced in 1998. Definite indication for H. pylori eradication is early gastric cancer in addition to the previous indications of peptic ulcer (PUD) including scar lesion and marginal zone B cell lymphoma (MALT type). Though treatment regimen was similar, Ja...