PURPOSE To report the outcome of pediatric patients with retinoblastoma refractory to traditional local therapy who were treated with indocyanine green (ICG)-enhanced thermotherapy. MATERIALS AND METHODS This is a retrospective review of a case series of 3 patients with bilateral retinoblastoma who were treated with ICG-enhanced thermotherapy after showing no response to conventional chemothe...

PURPOSE To assess a biological effect induced by temperature elevation during transpupillary thermotherapy (TTT). METHODS Six pigmented rabbits were anesthetized, and TTT was performed on the right eye using an 810-nm diode laser installed on a slit lamp (spot size, 1.3 mm; duration, 60 seconds; power, 92-150 mW). A series of laser pulses were aimed at the posterior pole of the retina. The le...

AIM To assess the effectiveness of transpupillary thermotherapy (TTT) for the treatment of classic and occult choroidal neovascularisation (CNV). METHOD In a retrospective, case selected, open label trial 44 eyes of 42 patients with CNV secondary to age related macular degeneration (ARMD) were studied. 44 eyes with angiographically defined CNV were treated with diode laser (810 nm) TTT. Laser...

PURPOSE To report the effect of subthreshold transpupillary thermotherapy (TTT) in treating serous detachment of the neurosensory retina secondary to chronic central serous chorioretinopathy (CCSC). METHODS Seven eyes from five patients with CCSC, persistent serous detachment of the neurosensory retina and a clinical course of between 12 and 60 months were treated. All eyes received large-spo...

1. Nyska A, Glovinsky Y, Belkin M, Epstein Y. Biocompatibility of the Ex-PRESS miniature glaucoma drainage implant. J Glaucoma. 2003;12: 275-280. 2. Mermoud A, Rivier D. The ExPRESS miniature glaucoma implant in combined surgery with cataract extraction: a prospective study. Paper presented at: Annual Meeting of the American Academy of Ophthalmology; October 2002; Orlando, Fla. 3. Wamsley S, Mo...

AIMS The effect of transpupillary thermotherapy (TTT) on human choroidal melanomas was investigated by means of histopathology. METHODS Before enucleation TTT was performed in 11 eyes with a xenon are photocoagulator with a red filter or a diode laser at 810 nm. The exposure time was 1 minute; the estimated temperature at the top of the tumour was about 65 degrees C. RESULTS Seven of 11 tum...

ranspupillary thermotherapy (TTT) is a technique in which heat s delivered to the posterior segment of the eye through the pupil sing a modified low power diode laser with a broad beam. This ethod uses infrared radiation to increase the temperature in the reated tissue up to 10 ◦C above baseline levels and it is been tried or the treatment of various intraocular tumors and choroidal neoasculari...