Pulmonary concerns in liver transplant candidates have intraoperative and outcome implications. Evolving MELD exception policies address transplant priority for problems such as hepatopulmonary syndrome, portopulmonary hypertension, and hemorrhagic hereditary telangiectasia. Other pulmonary issues such as refractory hepatic hydrothorax, advanced chronic obstructive lung disease (including alpha...

Hypertension developing after transplantation is characterized by widespread vasoconstriction including the kidney. Late resolution (mean, 29 +/- 4 months) of posttransplant hypertension has been observed in 15 (Group I) of 278 subjects monitored after liver transplantation. These studies were undertaken to define the systemic and renal changes associated with resolution, as compared with a gro...

Hypertension after renal transplantation is a strong predictor of patient and graft survival, but European guidelines for treatment of post-transplant hypertension have not yet been put forward. However, with the present knowledge, including data from recent intervention studies, there is a basis for future therapy guidelines. Here we address some important aspects of hypertension and its treat...

J Heart Lung Transplant 2008; 27: 466–468. 19 Olsson KM, Simon A, Strueber M, et al. ; Extracorporeal membrane oxygenation in nonintubated patients as bridge to lung transplantation. Am J Transplant 2010; 10: 2173–2178. 20 Wiklund L, Haraldsson A, Selimovic N, et al. Extracorporeal membrane oxygenation as a bridge to lung transplantation in a patient with persistent severe porto-pulmonary arter...

Once a patient receives kidney transplant, critical attention should be paid to ensure patient’s hemodynamic stability, they should be monitored for any side effects of the new medications and prevent infections that may jeopardize the renal allograft and patients’ general health. Medical problems such as diabetes and hypertension that may be medical complications of transplant immunosuppressio...

the goals of post-transplant management are to manage and treat postoperative complications, and develop a balanced long-term immunotherapy regimen that minimizes infection and side effects but controls rejection. while modern immunosuppressant regimes have reduced rates of graft loss due to rejection, they impart major risks for infection, growth failure, metabolic complications, and malignanc...

thiazide-sensitive Na-Cl cotransporters that is enhanced by the WNK and SPAK kinases. In normal subjects, calcineurin can inhibit the activity of WNK and SPAK through its phosphatase activity, but the regulatory activity of calcineurin can be inhibited both by tacrolimus and cyclosporine [2, 3], so explaining the volume expansion in CNI-treated transplant recipients. Therefore, post-transplant ...

Background & Aims: Hypertension, hyperuricaemia and nephrotoxicity are some common side-effects of Cyclosporine A (CsA) treatment in renal transplant recipients. Previous studies suggest that Calcium Channel Blockers (CCB) can increase serum level of CsA and may improve graft function in patients receiving CsA. The aim of this study was to evaluate the effects of Diltiazem and Amlodipine on cyc...

There is a strong rationale for renal denervation (RDN) of the native kidneys in kidney transplant recipients with treatment-resistant hypertension. We present a patient with a stable graft function, who underwent RDN for posttransplant therapy-resistant hypertension (24-h ambulatory blood pressure measurement (ABPM) 143/89 mmHg, while compliantly using five different antihypertensive agents). ...

introduction although renal transplantation from cadaver is common, living donors continue to be an important source of transplanted kidneys. recipients of living-donor kidneys demonstrate improved graft survival. in this study, we evaluated the outcomes of renal transplantation from cadaver, related donors and unrelated donors in isfahan. methods we evaluated all of the patients who underwent ...