The heterotrimeric kinase AMPK acts as an energy sensor to coordinate cell metabolism with environmental status in species from yeast through humans. Low intracellular ATP leads to AMPK activation through phosphorylation of the activation loop within the catalytic subunit. Other environmental stresses also activate AMPK, but it is unclear whether cellular energy status affects AMPK activation u...

Compensatory growth where animals compensate for time stress or transient nutritional or thermal stress by accelerating their growth rate is widespread. We know, however, relatively little about the evolution and ecological correlates of compensatory growth. For this we need studies on congeneric species with known phylogenetic relationships that also focus on the associated largely understudie...

Transient stress hyperglycemia in the setting of acute myocardial infarction is a frequent phenomenon. Its transient nature should not dissuade clinician from management elevated blood glucose patient after an ST-elevation infarction. This case presents adult with and evidence used to identify optimal pharmacologic secondary prevention.

conclusions the mechanism of mid-variant of dobutamine-induced stress cardiomyopathy remains unclear. we think that multiple mechanisms are involved and this risk should be considered in patients with comorbid psychiatric conditions and with use of centrally acting stimulants. case presentation we report a 48-year-old female with intermittent chest pain. her physical exam, cardiac enzymes and t...