Postpartum thyroiditis is one of the autoimmune thyroid dysfunctions which occurs during 12 months after delivery. Transient episodes of hypo­and hyperthyroidism in this disorder leads to maternal psychological and physical problems. Irreversible hypothyroidism occurs in a number of mothers. The prevalence and clinical course of the disease haven't been evaluated before, so this study was condu...

The reported incidence rate of primary congenital hypothyroidism (CH) has been increasing in the United States over the past 2 decades. We have considered the possibility that the inclusion of cases of transient hypothyroidism has inflated the reported incidence rate of CH. Assessing the effects of cases of transient hypothyroidism on the incidence rate is problematic, because the definitions, ...

OBJECTIVE To gain an insight into risk factors for hypothyroidism after subacute thyroiditis (SAT), we examined the correlation between initial laboratory and ultrasonographic findings and sequential thyroid dysfunction among treatment modalities. PATIENTS We reviewed retrospectively the medical records of 252 patients (26 men and 226 women) with SAT who consecutively visited our thyroid clin...

‘Screening window’, defined as the period between the development of the abnormal test result of NBS and development of symptoms in the infant, may vary from disorder to disorder. It will be most ideal to collect sample on fourth day of life. Samples can be collected from home by trained nurse/phlebotomist. There are many riders associated with interpretation of blood samples collected in the f...

Two siblings born to a mother with Wilson's disease, who was taking D-penicillamine, developed transient goitrous hypothyroidism. A prospective evaluation of 5 patients with Wilson's disease taking and not taking D-penicillamine for as long as 9.5 years showed subclinical hypothyroidism. D-penicillamine probably inhibited thyroperoxidase activity in utero in healthy infants and during childhood...

Studies in preterm infants have shown that prolonged treatment with topical iodine (multiple doses, often over multiple days) can transiently suppress thyroid function. However, it is uncertain if topical iodine exposure for very short periods of time can cause significant changes in thyroid function. We report two cases of transient hypothyroidism in preterm infants after short-term exposure t...

A 6 week old girl with transient congenital hypothyroidism is described. The hypothyroidism was associated with multiple applications of povidone iodine during pregnancy and lactation. This case illustrates the potential hazard of using topical solutions containing iodine during pregnancy and lactation.