Functional hydrogels show great potential for promoting the structural integration and signal transduction at bio/electronic interfaces.

Interferons (IFNs) are a family of small regulatory glycoproteins that play a central role in the defense against viral infections. Although IFNs have been initially discovered as antiviral factors, today they are known as an integral part of the cytokine network that affect a wide range of biological processes. IFNs exert their pleiotropic effects through their multisubunit cell surface recept...

there is increasing trend in using recombinant stem cells as novel therapeutic candidates in different diseases. these studies encompass different applications from targeted homing of mesenchymal stromal (stem) cells (msc), to arming them with different cytokines. resistance to transfection or transduction methods had urged researchers to look for better gene delivery alternates and optimizing ...

methods the current study generated two recombinant lentiviruses, plex-gcn and plex-gcp, bearing noxa and puma, respectively. transduction of both genes to hepatocarcinoma (hepg2) was verified using fluorescent microscopic analysis, western blotting, and quantitative real-time polymerase chain reaction (pcr). to evaluate the potential of noxa and puma to initiate apoptosis, a caspase-9 real-tim...

Wheat is a staple crop in China’s arid and semi-arid regions. Drought low nitrogen (LN) are two major constraints to wheat growth production. However, the molecular mechanism underlying response both drought LN stress remains unknown. Accordingly, we conducted proteomic study on roots of varieties, Chang6878 (drought tolerant) Shi4185 sensitive) compared differences between combined treatments....

An external redox signal delivered by ascorbic acid was used to trigger membrane translocation in a synthetic transduction system.

BASP1 is involved in signal transduction and cytoskeleton formation plays a tumor-promoting or tumor-suppressing role cancers. We found was overexpressed lung adenocarcinoma tissues...

signal regulatory proteins (sirp) belong to immunoglobulin super family (igsf) and relate to integrin signaling cascades. it has been shown that sirpa is expressed in a variety of cells including myeloid cells and neurons. in the present study the expression of this igsf member in articular chondrocytes was investigated. methods: using a panel of anti-sirpalpha antibodies, immunohistochemistry,...