PRIMARY OBJECTIVE To evaluate the extent to which the Personality Assessment Inventory (PAI) is confounded by symptoms that are transdiagnostic between psychopathology and neurological sequelae. METHODS Sixty-one adults with moderate-to-severe traumatic brain injury (TBI) completed the PAI over the first year post-injury. Items that discriminated brain-injured individuals from a normative sam...

If psychosis is a transdiagnostic dimension, the expression of which is governed by a dynamic set of contextual and emotional factors that are amenable to treatment, current approaches in psychiatric nosology and therapeutic research may need to be revised. The dominant approach to date is to clinically and conceptually situate psychotic symptoms in the construct of schizophrenia. However, schi...

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BACKGROUND Previous studies have demonstrated that acceptance and commitment therapy (ACT) is effective for depression and may be useful for complex transdiagnostic clients. AIMS To conduct a preliminary evaluation of whether ACT is feasible and effective when delivered by psychologists and non-psychologists for complex clients in a National Health Service (NHS) community mental health servic...

BACKGROUND Anxiety disorders share common vulnerabilities and symptoms. Disorder-specific treatment is efficacious, but few access evidence-based care. Administering transdiagnostic cognitive-behavioral therapy via the internet (iCBT) may increase access to evidence-based treatment, with a recent randomized controlled trial (RCT) providing preliminary support for this approach. This study exten...

BACKGROUND Increasingly, research supports the utility of a transdiagnostic understanding of psychopathology. However, there is no consensus regarding the theoretical approach that best explains this. Transdiagnostic interventions can offer service delivery advantages; this is explored in the current review, focusing on group modalities and primary care settings. OBJECTIVE This review seeks t...

BACKGROUND The purpose was to test the effectiveness of two transdiagnostic group interventions compared to care as usual (CAU) for patients with anxiety, depressive or stress-related disorders within a primary health care context. OBJECTIVES To compare the effects of cognitive-based-behavioural therapy (CBT) and multimodal intervention (MMI) on the quality of life and relief of psychological...

Emotion and pain are known to be intimately related, but treating co-occurring problems is still in its infancy mainly because we lack a clear theoretical understanding of the underlying mechanisms involved. This lack of understanding is problematic because treatment has proved challenging and co-occurring pain and emotional problems are associated with poor outcome, relapse, and greater sick a...