a-56-year-old woman underwent carpal tunnel release surgery under general anesthesia. thirty minutes after extubation, the patient complained of chest discomfort with dyspnea. swelling of the neck and upper anterior chest was observed. computed tomography of the chest showed tracheal rupture at the brachiocephalic trunk level, and bronchoscopy demonstrated a 5 cm linear tracheal defect in the p...

background: muscle relaxant agents usually use to facilitate tracheal intubation; however, sometimes limitations exist. magnesium (mg) sulfate is a candidate for muscle relaxant substitute. this study was designed to determine the effect of mg sulfate accompanied with propofol and fentanyl in patients undergoing ophthalmic surgery. materials and methods: in a double?blind randomized protocol an...

OBJECTIVE Tracheal diverticulum (DV) is an incidental finding in thoracic computed tomography examinations. Tracheal DV may be associated with chronic cough and chronic obstructive pulmonary disease (COPD). A few studies have investigated the relationship between tracheal DV and COPD. There is still no consensus on the relationship. The purpose of this study was to determine the incidence of tr...

Tracheal obstruction and tracheal injury can be life-threatening conditions in dogs and cats. Early identification of associated clinical signs and the use of appropriate diagnostic and therapeutic techniques are important to patient survival. Common causes of tracheal obstruction reported in the veterinary literature include tracheal foreign bodies and tracheal tumors. Tracheal injury has been...

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BACKGROUND This study evaluated the anti-allergic activity of corilagin and also postulates the possible mechanism of its action. MATERIAL AND METHODS Corilagin was given orally at dose of 10, 20, and 40 mg/kg/day. All the animals (guinea pigs, rats, and mice) were sensitized for allergy such as eosinophilia and leukocytosis induced by milk; degranulation of mast cell by compound 48/80; and pas...

The ethanol extract of Curculigo orchioides was evaluated for antiasthmatic activity by using various in vitro and in vivo animal models. In vitro models like isolated goat tracheal chain preparation and isolated guinea pig ileum preparation were studied to know basic mechanism by which extract shows relaxant activity. The study showed that extract is effective against histamine-induced contrac...

The purpose of this study was to determine the mechanism by which hydrogen peroxide (H2O2), an important inflammatory mediator, relaxes canine tracheal smooth muscle (CTSM). H2O2caused concentration-dependent relaxations of CTSM strips contracted with ACh or isotonic KCl [EC50 of 0.24 ± 0.04 (SE) and 0.23 ± 0.04 mM, respectively]. Indomethacin (10 μM) decreased the sensitivity of both KCl- and ...

In our study, surfactant protein (SP)-A was characterized in adult human trachea and bronchi. SP-A mRNA and protein were localized to serous cells in submucosal gland by in situ hybridization and immunohistochemistry, respectively. A 2.2 kb SP-A mRNA transcript was detected in tracheal tissues by Northern blot analysis. Primer extension analysis and gene-specific reverse transcriptase polymeras...