We have operated on nine patients suffering from benign or malignant tumours in the thoracic portion of the trachea. The main clinical symptom was difficulty in breathing, accompanied in the majority of cases by attacks of asphyxia, cough with mucous phlegm, and haemoptysis. The following operations were performed: circular resection of the trachea with end-to-end anastomosis, thoracic tracheot...

OBJECTIVE To identify genes expressed early in the formation of the mouse trachea that control patterning of tracheal cartilaginous rings. DESIGN The mouse larynx and trachea begin as an outpouching from the ventral foregut endoderm at embryonic day (E) 9. Digoxigenin-labeled RNA probes to putative tracheal patterning genes were generated by in vitro transcription. Embryos ranging in age from...

We investigated the ability of the muscarinic antagonist p-fluorohexahydrosiladifenidol to inhibit muscarinic agonist-induced contractions and phosphoinositide hydrolysis in the guinea pig ileum and trachea. This antagonist displayed higher potency at blocking oxotremorine-M-induced contractions of the ileum compared with those of the trachea. When estimated using a simple model for competitive...

Foreign body ingestion in trachea is a common occurrence children. However, pharyngeal foreign bodies are rare. Unlike the trachea, lumen of pharynx not kept patent by tracheal cartilage. Therefore, it difficult to distinguish from surrounding tissues. In addition, photographed lung window, so radiolucent objects may be seen, but mediastinal window sometimes appear invisible. If suspected, then...

SUMMARY A recent revival of global interest for reconstruction of long-segment tracheal defects, which represents one of the most interesting and complex problems in head and neck and thoracic reconstructive surgery, has been witnessed. The trachea functions as a conduit for air, and its subunits including the epithelial layer, hyaline cartilage, and segmental blood supply make it particularly ...

Tracheobronchopathia osteochondroplastica (TO) is a rare and usually benign disorder affecting the trachea and occasionally the bronchi. A case of TO was diagnosed in a 61 year old male farmer presenting with pulmonary infections and prolonged productive cough. A bronchoscopy revealed multiple nodular excrescences aong the anterolateral wall of the trachea and main bronchi. CT scans showed...

Introduction: Nitric Oxide is an important endogenous compound that acts as bronchodilator in trachea. Electromagnetic fields (EMF) affect nitric oxide level in different tissues. The interaction of nitrergic and cholinergic systems in airways has been reported. Therefore, the present study was performed to evaluate the interaction of cholinergic and nitrergic systems in the trachea of rats ...

A wide range of cellular developmental processes employ intercellular signaling via the Delta/Notch lateral inhibitory pathway to achieve stable spatial patterning. Recent genetic experiments have shown the importance of Delta/Notch lateral inhibition for regulating the number of tip cells in the tracheal primary branching of Drosophila. To examine the role of Delta/Notch regulation in the tip-...

objective(s) in the present study, the differences in the relaxant effects of aqueous, ethyl acetate and n-butanol fractions of rosa damascena on tracheal smooth muscle of guinea pigs were examined. materials and methods the relaxant effects of three cumulative concentrations of each fraction (0.1, 0.2 and 0.4 g%) in comparison with saline and three cumulative concentrations of theophylline (0....

Here, we report a fetus with a rare aortic arch anomaly with left aortic arch and right ductus arteriosus, which has not been reported so far. In this condition, the aorta extends to the left of the trachea as in normal, while the ductus arteriosus extends to the right of the trachea and joins the descending aorta posterior to the trachea, with a cross-ribbon sign.