An important issue in the use of expert systems is the so-called brittleness problem. Expert systems model only a limited part of the world. While the explicit management of uncertainty in expert systems mitigates the brittleness problem, it is still possible for a system to be used, unwittingly, in ways that the system is not prepared to address. Such situation may be detected by the method of...

BACKGROUND: Pesticide toxicity is a serious problem in poor and developing countries agricultural communities, including Indonesia.
 AIM: This study aims to design an effort of pesticide prevention.
 METHODS: participation action research look, think, cycle use process as qualitative study. The participants were taken by purposive technique data collected with focus group discussion, ...

Abstract Muscle-invasive bladder cancer is most frequently diagnosed in older patients and the presence of multimorbidity frailty common. This means that many are unsuitable for definitive treatment with radical cystectomy/(chemo)radiotherapy at risk poor survival outcomes considerable disease-related morbidity. Screening tools functional status may be useful to determine appropriate a...

AIMS To assess knowledge, attitude, practice, and toxicity symptoms associated with pesticide use and exposure among 189 farm workers in the Gaza Strip. METHODS A cross section of agricultural farm workers in the Gaza Strip were asked to fill in a questionnaire on knowledge, attitudes, practice towards pesticide use, and associated toxicity symptoms. RESULTS Farm workers reported high level...

Manganese (Mn) is an essential micro-nutrient for plants, but flooded rice fields can accumulate high levels of Mn2+ leading to Mn toxicity. Here, we present a genome-wide association study (GWAS) to identify candidate loci conferring Mn toxicity tolerance in rice (Oryza sativa L.). A diversity panel of 288 genotypes was grown in hydroponic solutions in a greenhouse under optimal and toxic Mn c...

Colchicine has a low therapeutic index. Its toxic effects generally occur at doses ≥ 0.5 mg/kg. We present the case of a 39-year-old female with toxicity following ingestion of 0.28 mg/kg. The patient presented to the emergency department (ED) with severe nausea, vomiting, and abdominal pain following an intentional multidrug ingestion that included colchicine, indomethacin, and zopiclone. Desp...

BACKGROUND Patients with large prostate volumes have been shown to have higher rates of genitourinary and gastrointestinal toxicities after conventional radiation therapy for prostate cancer. The efficacy and toxicity of stereotactic body radiation therapy (SBRT), which delivers fewer high-dose fractions of radiation treatment, is unknown for large prostate volume prostate cancer patients. We r...

Dysphagia is an unusual symptom in the clinical course of lung carcinoma. When it appears, it is necessary to differentiate between regional dissemination, drug toxicity, opportunistic infection and, most rarely, metastatic dissemination to the brain stem. Magnetic resonance imaging (MRI) is the best diagnostic option to exclude this last possibility. We present a male patient with progressive ...

PURPOSE To describe the frequency of acute and late Radiation Therapy Oncology Group (RTOG) urinary toxicity, associated predictive factors, and resolution of International Prostate Symptom Score (IPSS) in 712 consecutive prostate brachytherapy patients. METHODS AND MATERIALS Patients underwent implantation between 1998 and 2003 (median follow-up, 57 months). The IPSS and RTOG toxicity data w...

Availability and uptake of heavy metals (Zn, Cu, Fe, Al, Cr, Ni) by mung bean grown on coal mine spoil was studied. The experiment was carried out as a pot culture experiment using garden soil and different proportion of coal mine spoil. The heavy metals were transported to roots then shoot and were found in traces in the fruits. No toxicity symptom was reported during vegetative as well as rep...