Objective: Metals including arsenic, lead, mercury, and cadmium are toxic can increase cardiovascular disease risk. High-sensitivity C-reactive protein (hs-CRP) is a biomarker for inflammation This study will evaluate the association between urinary speciated cadmium, mercury blood values of hs-CRP in United States adult population. Methods: A cross-sectional using 2015-2016 NHANES dataset, con...

The concept of toxic leadership has been widely investigated in diverse settings with most contributors agreeing its impact on followers can have negative effects to the victim's well-being, job satisfaction, group productivity and organisational commitment. However, not yet sufficiently researched tertiary educational settings, this case, specifically Chilean higher education. This paper explo...

Colicine V has been obtained from the culture medium in which the colicinogenic bacillus E. coli K357 L_T is grown. The material is electrophoretically homogeneous and proves to be a lipocarbohydrate protein complex identical with the type-specific O antigen of the parent bacillus. Colicine V is toxic both for mice and for rabbits and readily stimulates the elaboration of precipitins and bacter...

Alcohol abuse causes progressive toxicity and degeneration in liver and brain due to insulin resistance, which exacerbates oxidative stress and pro-inflammatory cytokine activation. Alcohol-induced steatohepatitis promotes synthesis and accumulation of ceramides and other toxic lipids that cause insulin resistance. Ceramides can readily cross the blood-brain barrier, and ceramide exposure cause...

Background: There are few published reports on the clinical characteristics of auto-immune thyroid disease in the African. Objectives: To assess the clinical features Thyrotropin Receptor (TR) and Thyroid Peroxidase (TPO) antibodies in Toxic Graves’ and Spontaneous Primary Hypothyroidism (SPH). Methods: Cross sectional study of black African patients with Toxic Graves’ and SPH attending an Endo...

Interstrand DNA-DNA cross-links are highly toxic to cells because these lesions block the extraction of information from the genetic material. The pathways by which cells repair cross-links are important, but not well understood. The preparation of chemically well-defined cross-linked DNA substrates represents a significant challenge in the study of cross-link repair. Here a simple method is re...

purpose: to describe the clinical signs, diagnosis and treatment of toxic keratopathy in a patient who abused tetracaine drops. case report: a 32-year-old man was referred to the emergency ward of our center with persistent corneal epithelial defect associated with a ring infiltrate in the corneal stroma, without any history of ocular trauma or contact lens use. the patient was hospitalized and...

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a rapid and reproducible method is described that employs solid phase extraction (spe) using dichloromethane, followed by gas chromatograph-mass spectrometry for the determination of toxic toluene, xylene and cumene (txc) from different lake water of dhaka mega city of bangladesh. the method was applied to detect and quantify txc in water samples collected from surface and 30 cm depth of water....