Toxic affections associated with pregnancy have been reported in several species of animals, notably the sheep (2)and guinea pig (3); it is also common knowledge among breeders that overfat animals of all kinds are apt to die during gestation or parturition, but the exact nature and pathogenesis of these disorders is not known. A highly fatal affection associated with pregnancy also occurs in t...

The vascular and renal disorders of the last trimester of pregnancy are classified by the University Obstetrical Service in the following groups: specific toxemia, pre-existing essential hypertension, pre-existing glomerulonephritis and specific toxemia superimposed on pre-existing hypertension or nephritis (1). Specific toxemia is clinically characterized by the rather abrupt appearance of hyp...

The clinical and pathological manifestations of a disease occurring in the late stages of pregnancy or following parturition in the guinea pig are described. The similarity of this disease to toxemia of pregnancy in the rabbit is discussed. The disease appears to be of endogenous origin and is in some way associated with a disordered metabolism occurring at about the time of parturition.

Persistence of elevated blood pressure in toxemia of pregnancy following autonomic blockade with tetraethylammonium chloride (TEAC) has been reported previously by the authors ( 1 ). Subsequently many of the patients studied were treated with subcutaneous veratrum viride with consistent depressor effects. The apparent opposing actions of these two drugs in toxemia, together with a suggestion th...

Certain complications of pregnancy, e.g., threatened spontaneous abortion, toxemia, emesis, and anemia, were studied in pregnant women living in industrial areas contaminated by smelters and the petrochemical industry. Exposure to lead or aromatic hydrocarbons was assessed in parallel by the determination of these agents or their metabolites in blood and urine. Comparison of respective exposure...

The present work aimed to study the behavior of acute phase proteins (haptoglobin, serum amyloid A, acid soluble glycoprotein, fibrinogen, and albumin) in fasting-induced pregnancy toxemia in goats and their relationship with classical indicators of this disorder such as beta-hydroxybutyrate and nonesterified fatty acids in the blood and decreased urine pH and ketonuria. Twelve adult Murciano-G...

Observations on the treatment of infertile rabbits with antuitrin "B." Proc. Soc. exp. A lethal mutation in the rabbit with stigmata of an acromegalic disorder. Science, 81: 25, 1935. Rabbit pox. III. Report on an epidemic with especial reference to epidemiological factors. The influence of intra-uterine factors on the fetal weight of rabbits. Toxemia of pregnancy in the rabbit. II. Etiological...