background: hyperbilirubinemiais a common problem in newborn infants. it can progress to kernicterus in severe forms, unless an intervention is initiated. the objective of this study was to compare the efficacy of clofibrate with phenobarbital in full-term neonates with nonhemolytic jaundice. methods: this double blind clinical trial study was performed on 60 neonate who were divided randomly i...

<b><i>Introduction:</i></b> Transcutaneous bilirubin (TcB) measurement offers a noninvasive approach for screening; however, its accuracy in preterm infants is unclear. This study determined the agreement between TcB and total serum (TSB) among infants. <b><i>Methods:</i></b> A multisite prospective cohort was conducted at 3 NICUs Ontario, Canada,...

PURPOSE To investigate renal function estimated by markers in full-term newborns with hyperbilirubinemia. METHODS A total of 332 full-term newborns with hyperbilirubinemia and 60 healthy full-term newborns were enrolled. Total serum bilirubin, serum creatinine (Cr), serum blood urea nitrogen (BUN), serum cystatin C (Cys-C), urinary beta-2-microglobulin (β 2MG) index, and urinary N-acetyl-beta...

RECT SPECTIt( )PHOTOMETRY of serum bihrubin implies the det ation of Serum brilirubin at or near its absorption maxiumuni at m l)y means of a spectrophotometer calibrated with bilirubin ndards, with a correction for the presence of hemolysis intmoed. A spectrophotomnetric method for hilirubin evaluation has three antages: 1. It serves as a check on methods that employ the van deli Bergh gent. 2...

OBJECTIVE The recognition, follow-up, and early treatment of neonatal jaundice has become more difficult, since the earlier discharge of newborns from hospitals has become common practice. This prospective study was undertaken to identify the newborns at risk for developing significant hyperbilirubinemia later during the first days of life by measuring the serum bilirubin levels of the first 5 ...

Background: The effects of magnesium physiology are contradictory to the neurotoxic effect of bilirubin, but the relationship between magnesium level and hyperbilirubinemia in neonates has not been well studied. In this study, we investigated the relationship between serum magnesium level and hyperbilirubinemia and hyperbilirubinemia complications at the Children’s Medical Center. Methods: In ...