background pegylated interferon alfa plus ribavirin protocol is currently considered the most efficient hepatitis c treatment. however, no evidence of costs comparison among common viral genotypes has been published. objectives we aimed to assess core drivers of hepatitis c medical care costs and compare cost effectiveness of this treatment among patients infected by hepatitis c virus with geno...

in this study the location routing problem with fuzzy parameters is taken into account, this problem involves determining the location of the depots and routing of the vehicles in order to serve the customers. in this study a location routing problem with fuzzy travel times and due dates is considered and two objective models are proposed. the considered objectives are minimizing the total cost...

OBJECTIVE The purpose of this study was to compare the cost-effectiveness of laparoscopic-assisted vaginal hysterectomy to traditional total abdominal hysterectomy and total vaginal hysterectomy with regard not only to direct hospital costs but also to indirect costs. STUDY DESIGN This was a combined retrospective cohort study (Canadian Task Force classification II-2) that was conducted in a ...

results the total number of time-loss injuries and matches missed rose from 129 and 506 respectively in 2008 - 2009 to 202 and 1110 in 2010 - 2011. following the introduction of ‘minimum medical standards’, both categories decreased (significantly for matches missed). these time-loss injuries and matches missed led to high costs of up to aud$ 37,317,029.29 (2012 - 2013 season). the same trend w...

according to importance of cirrhosis of the liver and the lack of information about the economic burden of the disease, we performed this study to estimate the economic burden of liver cirrhosis in iran in 2011.the cost-of-illness method, based on the human capital theory, has been used. both direct and indirect costs have been estimated using a prevalence approach and bottom-up method. the inp...

OBJECTIVE To determine the annual direct, indirect and total costs and predictors of costs in patients with systemic lupus erythematosus (SLE). METHODS One hundred and five patients with SLE completed questionnaires on health-care utilization and employment history. Predictors of costs were determined by multiple regression analyses using direct, indirect and total costs as outcome variables....