AbstractPaederus dermatitis is an irritant contact dermatitis due to accidental contact by a beetle belonging to the genus paederus. In this study, clinical efficacies of S. ebulus fruit extract solution in patients affected by paederus dermatitis were evaluated. A randomized double-blind, prospective, placebo-controlled clinical trial was performed in 62 patients with clinical symptoms and sin...

Studies in preterm infants have shown that prolonged treatment with topical iodine (multiple doses, often over multiple days) can transiently suppress thyroid function. However, it is uncertain if topical iodine exposure for very short periods of time can cause significant changes in thyroid function. We report two cases of transient hypothyroidism in preterm infants after short-term exposure t...

Introduction: Deferoxamine mesylate increases hypoxia inducible factor-1 alpha transactivation by preventing iron-catalyzed reactive oxygen stress, so it can be used to improve diabetic ulcer healing. This study was undertaken develop and physicochemical properties of topical deferoxamine-loaded solid lipid nanoparticles.
 Method: Solid nanoparticles were prepared using cold homogenization...

Topical medication administration is the simplest and most convenient method of delivering localised drugs to any part body via ophthalmic, rectal, vaginal, cutaneous channels. These are used in a wide range cosmetic dermatological preparations on both healthy sick skin. Drugs applied topically have an effect at application site or systemic effects. The goal this study was develop characterise ...